2018
DOI: 10.1007/s11606-018-4633-1
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Mind the Gap: Putting Evidence into Practice in the Era of Learning Health Systems

Abstract: Due to the increasing amount of available published evidence and the continual need to apply and update evidence in practice, we propose a shift in the way evidence generated by learning health systems can be integrated into more traditional evidence reviews. This paper discusses two main mechanisms to close the evidence-to-practice gap: (1) integrating Learning Health System (LHS) results with existing systematic review evidence and (2) providing this combined evidence in a standardized, computable data forma… Show more

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Cited by 77 publications
(81 citation statements)
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“…Although this barrier was not frequently stated in interviews with IDx experts, it is implicit in the historical difficulty in bringing attention to and improving diagnoses . As our LHS interviewees commented, we are in desperate need of system‐based solutions that catalyze K2P, institutionalizing the pipeline—curation, management, and dissemination—that translates evidence‐based medicine and ML algorithms into the clinical exam room …”
Section: Discussionmentioning
confidence: 99%
“…Although this barrier was not frequently stated in interviews with IDx experts, it is implicit in the historical difficulty in bringing attention to and improving diagnoses . As our LHS interviewees commented, we are in desperate need of system‐based solutions that catalyze K2P, institutionalizing the pipeline—curation, management, and dissemination—that translates evidence‐based medicine and ML algorithms into the clinical exam room …”
Section: Discussionmentioning
confidence: 99%
“…In the commentary by Guise et al, the authors describe a learning cycle for learning health systems in which evidence is rapidly generated, integrated into practice, and further evidence can be generated for further medical and clinical insights. 1 The novel aspect suggested is the archiving of data, whether from clinical trials, systematic reviews and metaanalyses, and other study types, in such a manner that enables rapid reproducibility and continuous updating of medical evidence. In the clinical world, this is indeed a novel approach: the realities of healthcare delivery-the fragmented systems of care, misaligned values and incentives, slow adoption of new effective technologies, or the recognizable black box in which clinicians enter burdensome amounts of data without the feedback of intelligent insights-could all significantly benefit from the findability, accessibility, interoperability, and reusability of data in all of its forms.…”
Section: T O the Editorsmentioning
confidence: 99%
“…The positive feedback regarding these products suggests that they may be a useful step toward bridging the gap between evidence production and use in health systems. 12 Overall, based on these pilot projects, we learned the following:…”
Section: Recommendationsmentioning
confidence: 99%