Purpose of report This report summarizes nine Evidence-based Practice Center (EPC) pilot projects that developed companion products intended to accelerate the uptake and implementation of evidence from EPC reviews in health systems. Key messages • EPCs developed nine companion products, which included dissemination products (e.g., short report summaries), interactive data visualization products (e.g., interactive maps), and implementation products (e.g., electronic health tools and decision aids) to help health systems use the findings from EPC reviews. • Developing companion products to EPC evidence reviews required additional time, resources and information, and expertise. • Before starting an evidence review, working with health systems to understand the needs and decisional dilemma they are facing will allow systematic reviewers to incorporate additional context specific information to improve usefulness for health systems. • Companion products may help health systems use findings from AHRQ evidence reviews. Products should prioritize clear writing, meaningful tables and graphs, and tailor the evidence to the needs of a partner. iii This report is based on research conducted by the Agency for Healthcare Research and Quality (AHRQ) Scientific Resource Center, funded through the following contract: Scientific Resource Center III (290-2017-00003C). The findings and conclusions in this document are those of the authors, who are responsible for its contents; the findings and conclusions do not necessarily represent the views of AHRQ. Therefore, no statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services. None of the investigators have any affiliations or financial involvement that conflicts with the material presented in this report. The information in this report is intended to help EPCs and AHRQ understand how EPC reports can be improved to benefit health-system decision making. This report is not intended to be a substitute for the application of clinical judgment. Anyone who makes decisions concerning the provision of clinical care should consider this report in the same way as any medical reference and in conjunction with all other pertinent information, i.e., in the context of available resources and circumstances presented by individual patients. This report is made available to the public under the terms of a licensing agreement between the authors and the Agency for Healthcare Research and Quality. This report may be used and reprinted without permission except those copyrighted materials that are clearly noted in the report. Further reproduction of those copyrighted materials is prohibited without the express permission of copyright holders. AHRQ or U.S. Department of Health and Human Services endorsement of any derivative products that may be developed from this report, such as clinical practice guidelines, other quality enhancement tools, or reimbursement or coverage policies, may not be stated or implied.