Minimally Invasive Spinal Treatment (MIST)—A New Concept in the Treatment of Spinal Diseases: A Narrative Review

Ishii, Ken; Watanabe, Goichi; Tomita, Takashi; Nikaido, Takuya; Hikata, Tomohiro; Shinohara, Akira; Nakano, Masato; Saito, Takanori; Nakanishi, Kazuo; Morimoto, Tadatsugu; Isogai, Norihiro; Funao, Haruki; Tanaka, Masato; Kotani, Yoshihisa; Arizono, Takeshi; Hoshino, Masahiro; Sato, Koji

doi:10.3390/medicina58081123

Cited by 6 publications

(8 citation statements)

References 37 publications

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“…Nowadays, minimally invasive spinal stabilization (MISt) has been applied to FBSS to prevent invasion to the back muscles and neural elements. MISt is a part of minimally invasive spine surgery that stabilizes the spine using minimally invasive spinal fusion techniques and dynamic stabilization techniques to correct imbalances caused by spinal instability, intervertebral instability, and spinal deformity [ 17 , 18 ]. MISt includes minimally invasive techniques—MIS-TLIF [ 19 , 20 ], LLIF including extreme lateral interbody fusion (XLIF) [ 10 , 11 , 12 , 13 ], oblique lumbar interbody fusion (OLIF) [ 21 , 22 ], etc.…”

Section: Discussionmentioning

confidence: 99%

A Comparative Clinical Study of Lateral Lumbar Interbody Fusion between Patients with Multiply Operated Back and Patients with First-Time Surgery

et al. 2023

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Background and Objectives: Patients with multiply operated back (MOB) may suffer from persistent lower-back pain associated with back muscle damage and epidural fibrosis following repeated back surgery (Failed Back Spinal Syndrome). Lateral lumbar interbody fusion (LLIF) is considered to be favorable for MOB patients. However, little scientific research has been carried out for this issue due to variety of the pathogenesis. The purpose of this study was to compare the clinical results of MOB patients and first-time surgery patients who underwent LLIF for lumbar spinal stenosis with degenerative scoliosis and/or degenerative spondylolisthesis (spinal instability). Materials and Methods: LLIF was performed for lumbar spinal stenosis with spinal instability in 55 consecutive cases of single hospital (30 males, 25 females, average age: 69). Clinical outcomes were compared between the MOB patient group (MOB group) and the first surgical patient group (F group). We evaluated the Japanese Orthopaedic Association (JOA) scores and JOA Back Pain Evaluation Questionnaire (JOABPEQ) before and 2 years after surgery. MOB patients were defined as those who have had one or more lumbar surgery on the same intervertebral or adjacent vertebrae in the past. Results: There were 20 cases (12 males, 8 females, average age: 71) in MOB group, and 35 cases (19 males, 16 females, average age: 68) in the F group. There was no significant difference between the two groups in terms of age, sex, number of intervertebral fixations, modic change in fused intervertebral end plate, score of brief scale for evaluation of psychiatric problem, lumbar lordosis, and sagittal vertical axis before and after surgery. The preoperative JOA scores averaged 12.5 points in the MOB group and averaged 11.6 points in the F group. The postoperative JOA scores averaged 23.9 points in the MOB group and averaged 24.7 points in the F group. The preoperative JOABPEQ averaged 36.3 points in the MOB group and averaged 35.4 points in the F group. The postoperative average JOA score was 75.4 in the MOB group and 70.2 in the F group. Conclusions: Based on the results, there was no significant difference in clinical outcomes of the two groups, and there was no new residual lower-back pain. Thus, we considered that LLIF one option for patients with MOB.

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Section: Discussionmentioning

confidence: 99%

A Comparative Clinical Study of Lateral Lumbar Interbody Fusion between Patients with Multiply Operated Back and Patients with First-Time Surgery

et al. 2023

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“…Approaches that render the management of spinal metastases less invasive, including radiotherapy, BKP, and MISt, are collectively referred to as MIST ( 17 ). MIST can provide an improvement in prognosis for patients ineligible for conventional invasive surgery ( 17 , 27 ). MIST have expanded the indications for surgery and become essential for patients with cancer.…”

Section: Advances In Treatments For Spinal Metastasismentioning

confidence: 99%

“…Advances in drug treatment, radiotherapy, and minimally invasive spine surgery (MISS) have expanded the management alternatives for patients with spinal metastases. Therefore, minimally invasive spine treatment (MIST) ( 17 ), a concept describing the minimally invasive management of spinal diseases and including conservative treatment, radiotherapy, and less invasive conventional surgery, has been proposed.…”

Section: Introductionmentioning

confidence: 99%

A new era in the management of spinal metastasis

Morimoto,

Toda,

Hakozaki

et al. 2024

Front. Oncol.

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Despite the recent advances in cancer treatment, the incidence of patients with spinal metastases continues to grow along with the total number of cancer patients. Spinal metastases can significantly impair activities of daily living (ADL) and quality of life (QOL), compared with other types of bone metastases, as they are characterized with severe pain and paralysis caused by skeletal-related events. Reduced ADL can also lead to treatment limitations as certain anticancer agents and radiation therapy are not compatible treatments; thus, leading to a shorter life expectancy. Consequently, maintaining ADLs in patients with spinal metastases is paramount, and spine surgeons have an integral role to play in this regard. However, neurosurgeon, orthopedic and spinal surgeons in Japan do not have a proactive treatment approach to spinal metastases, which may prevent them from providing appropriate treatment when needed (clinical inertia). To overcome such endemic inertia, it is essential for 1) spine surgeons to understand and be more actively involved with patients with musculoskeletal disorders (cancer locomo) and cancer patients; 2) the adoption of a multidisciplinary approach (coordination and meetings not only with the attending oncologist but also with spine surgeons, radiologists, rehabilitation specialists, and other professionals) to preemptive treatment such as medication, radiotherapy, and surgical treatment; and 3) the integration of the latest findings associated with minimally invasive spinal treatments that have expanded the indications for treatment of spinal metastases and improved treatment outcomes. This heralds a new era in the management of spinal metastases.

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“…Posterior lumbar interbody fusion (PLIF)/transforaminal lumbar interbody fusion (TLIF) are globally recognized surgical techniques, with documented reports on their therapeutic efficacy and safety 1 …”

Section: Introductionmentioning

confidence: 99%

“…

Posterior lumbar interbody fusion (PLIF)/transforaminal lumbar interbody fusion (TLIF) are globally recognized surgical techniques, with documented reports on their therapeutic efficacy and safety. 1 These surgeries are aimed at bony fusion between vertebrae; therefore, rare complications can arise from spine surgery. This can cause damage to adjacent visceral structures such as the intestines and blood vessels during disc curettage and cage/bone grafting.

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confidence: 99%

Anterior graft migration in posterior lumbar interbody fusion: A case report and literature review

Hashimoto,

Hirata,

Tsukamoto

et al. 2023

Clinical Case Reports

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Key Clinical MessageSpine surgeons should be aware of the possibility of anterior displacement of the grafted bone during PLIF and the potential for severe complications that may arise because of such displacement so that preparations can be made for a proper response.AbstractWe report two cases of anterior displacement of the grafted bone after posterior lumbar interbody fusion (Graphical Abstract A‐D). The patients did not require additional surgery. The anterior migration of grafted bone or cage can cause damage to anterior organs and blood vessels. Therefore, a careful surgical procedure is necessary.

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Minimally Invasive Spinal Treatment (MIST)—A New Concept in the Treatment of Spinal Diseases: A Narrative Review

Cited by 6 publications

References 37 publications

A Comparative Clinical Study of Lateral Lumbar Interbody Fusion between Patients with Multiply Operated Back and Patients with First-Time Surgery

A Comparative Clinical Study of Lateral Lumbar Interbody Fusion between Patients with Multiply Operated Back and Patients with First-Time Surgery

A new era in the management of spinal metastasis

Anterior graft migration in posterior lumbar interbody fusion: A case report and literature review

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