Minimum alveolar concentration of sevoflurane for tracheal extubation in children

Abstract

Tracheal extubation in 50% of anaesthetized children age 2-10 yr may be accomplished without coughing or moving at 2.3% end-tidal concentration of sevoflurane.

Airway responses to desflurane during maintenance of anesthesia and recovery in children with laryngeal mask airways

“…We anticipated that this could be a problem when we designed this study because the ED 95 value for removing the LMA during desflurane anesthesia in children was unknown. The ED 95 for removing the LMA after sevoflurane anesthesia and for removing a tracheal tube after desflurane and sevoflurane are approximately 0.8–0.9 MAC (12,20,21). This suggests that the ED 95 for removing the LMA during deep desflurane anesthesia in children should be ∼8%.…”

Sevoflurane in Paediatric Anaesthesia

“…Sevoflurane increases heart rate [46][47][48]131] to a greater extent than halothane during induction, but causes fewer instances of arrhythmias [46,74,75,132] and bradycardia [48,74,133] during anaesthesia. These differences were statistically significant in the trials cited.…”