Mirtazapine Therapy for Dysgeusia in an Elderly Patient

Padala, Kalpana P.; Hinners, Cheryl K.; Padala, Prasad R.

doi:10.4088/pcc.v08n0310b

Cited by 10 publications

(3 citation statements)

References 14 publications

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“…Difficulty in swallowing in various diseased conditions or due to a large size of unit dosage can be reduced by developing ODTs. 4,5 ODTs are solid dosage forms that disintegrate in oral cavity releasing drug contents which dissolve or disperse with the aid of saliva. 6 These exist in different forms such mouth dissolving tablets, melt-in-mouth, fast dissolving drug delivery, rapid melt tablets, porous tablets, quick dissolving tablets etc.…”

Section: Introductionmentioning

confidence: 99%

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Comparative Study of Various Polymeric Superdisintegrants on the Design and Evaluation of Novel Antihypertensive Orodispersible Tablets

et al. 2016

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Superdisintegrants are major participants in orodispersible tablets (ODTs) to accord fast disintegration. A myriad of natural and synthetic disintegrants have been utilized. In present work, antihypertensive ODTs of atenolol and atorvastatin calcium were prepared in two groups based on a combination of superdisintegrants, i.e., F1-F15 (sodium starch glycolate and pregelatinized starch) and F16-F30 (croscarmellose sodium and Kyron T 134 ). The direct compression method was adapted along with the effervescence and sublimation approach. The effect of manufacturing process, concentration, and type of superdisintegrants on characteristics of ODTs was observed. Rheological and compatibility studies such as Fourier transform infrared spectroscopy and differential scanning calorimetry were performed for drug and other markers. Scanning electron microscopy proved the presence of pores on the tablet surface. Postcompression parameters such as tablet hardness, thickness, diameter, weight variation, friability, disintegration time, dissolution studies, wetting time, wetting volume, water absorption ratio, modified disintegration, uniformity of contents, and stability studies were carried out. Finally, results were statistically evaluated by the application of one-way analysis of variance test. Based on parameters formulation, F23 designed by the sublimation technique declared best one among all. C 2015 Wiley Periodicals, Inc. Adv Polym Technol 2015, 0, 21562; View this article online at wileyonlinelibrary.com.

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Section: Introductionmentioning

confidence: 99%

“…ODTs have also been used for solubility enhancement of poorly water‐soluble drugs, e.g., atenolol, rosuvastatin calcium, acyclovir, etc. Difficulty in swallowing in various diseased conditions or due to a large size of unit dosage can be reduced by developing ODTs …”

Section: Introductionmentioning

confidence: 99%

Comparative Study of Various Polymeric Superdisintegrants on the Design and Evaluation of Novel Antihypertensive Orodispersible Tablets

et al. 2016

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“…Various superdisintegrants like kyron T134, crospovidone, pregelatinized starch, sodium starch glycolate, croscarmellose sodium etc., along with hydrophilic carriers such as β-cyclodextrin etc., are used to enhance solubility and consequently, patient compliance [11][12][13][14]. Rosuvastatin calcium (RST), belongs to BCS class II drugs having low solubility and high permeability.…”

Section: Introductionmentioning

confidence: 99%