MitraClip and mitral annuloplasty device as a bridge to transplantation

Abstract

A 42-year-old man with dilated cardiomyopathy and endstage heart failure was evaluated for heart transplantation. He received a MitraClip and Carillon annuloplasty device for functional mitral regurgitation as palliation for his heart failure. Subsequently, he underwent successful heart transplantation.

MitraClip procedure as ‘bridge to list’, the ultimate therapeutic option for end‐stage heart failure patients not eligible for heart transplantation due to severe pulmonary hypertension

“…Although the role of MitraClip as ‘bridge to transplant’ has already been reported, 5 – 7 this is a proof of concept case series demonstrating, for the first time, the role of the MitraClip procedure as ‘bridge to list’ in end-stage HF patients not eligible or at high risk for HTx due to elevated PVR with unsatisfactory response to vasodilator challenge. In all three patients, the MitraClip procedure was followed by a sustained reduction of PVR, allowing them to become eligible for HTx.…”

Transcatheter therapies for secondary mitral regurgitation in advanced heart failure: what are we aiming for?

“…Further analysis found a positive impact of TMVr in terms of lower pulmonary artery pressures and resistances, with the consequence of including patients previously ineligible for this therapy on the HTx list (BTC) [25,26]. The first results of the feasibility of a BTT strategy were described after the implantation of MitraClip alone or in combination with the Carillon device (Cardiac Dimensions, Kirkland, WA, USA) [27,28]. The achievement of great clinical and hemodynamic benefits can even lead to recovery such as removing the patient from the HTx list (BTR) [29].…”