Mitral valve motion assessed by high-speed video camera in isolated swine heart

Saito, Shu; Araki, Yoshimori; Usui, Akihiko; Akita, Toshiaki; Oshima, Hideki; Yokote, Jun; Ueda, Yuichi

doi:10.1016/j.ejcts.2006.07.021

Cited by 20 publications

(26 citation statements)

References 22 publications

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“…An Ex vivo study (Saito et al 2006) presents results on influence of preload as mean left atrial pressure condition on mitral valve opening. Additional testing should be performed to understand flow through the native mitral valve as well as mitral bioprosthesis.…”

Section: Discussionmentioning

confidence: 99%

Geometrical orifice area compared to effective orifice area of valvular mitral bioprosthesis:in vitrostudy

Evin¹,

Guivier-Curien²,

Tanné³

et al. 2012

Computer Methods in Biomechanics and Biomedical Engineering

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Section: Discussionmentioning

confidence: 99%

Geometrical orifice area compared to effective orifice area of valvular mitral bioprosthesis:in vitrostudy

Evin¹,

Guivier-Curien²,

Tanné³

et al. 2012

Computer Methods in Biomechanics and Biomedical Engineering

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“…The main drawback of the Heaviside formulation is that it does not take into account physiological time scale of the valve aperture (Saito et al, 2006). Therefore, the initial model is not able to fully capture valve dysfunctions.…”

Section: The Mitral Valve Modelmentioning

confidence: 99%

“…The normal motion of the mitral valve during a cardiac cycle has been analyzed by Saito et al (Saito et al, 2006). The qualitative normal mitral aperture evolution during the diastole is given in Figure 4.…”

Section: The Mitral Valve Modelmentioning

confidence: 99%

Mathematical model of the mitral valve and the cardiovascular system Application for studying and monitoring valvular pathologies

Paeme

Moorhead

Chase

et al. 2010

UKACC International Conference on CONTROL 2010

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A cardiovascular and circulatory system (CVS) model has been validated in silico, and in several animal model studies. It accounts for valve dynamics using Heaviside functions to simulate a physiologically accurate scale of the valve aperture dynamics, and therefore does not fully capture valve dysfunction, particularly where the dysfunction involves partial closure. This research describes a new closed-loop CVS model, including a description of the progressive aperture of the mitral valve, and is valid over the full cardiac cycle. This new model is solved for a healthy and diseased mitral valve.

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“…The main drawback of the Heaviside formulation is that it does not take into account physiological time scale of the valve aperture [17]. Therefore, the initial minimal CVS model is not able to fully capture valve dysfunctions.…”

Section: The Mitral Valve Modelmentioning

confidence: 99%

“…It is therefore testing the aggregation of elements tested individually in previous studies. The normal motion of the mitral valve during a cardiac cycle has been analyzed by Saito et al [17]. From this qualitative analysis and quantitative values from literature [19][20][21][22][23][24], normal mitral aperture evolution as well as transmitral blood flow during the diastole has been reconstructed, regarding the driving pressure.…”

Section: Static Response Validationmentioning

confidence: 99%

Structural model of the mitral valve included in a cardiovascular closed loop model. Static and dynamic validation

Paeme

Pironet

Chase

et al. 2012

IFAC Proceedings Volumes

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A minimal cardiovascular system (CVS) model including mitral valve dynamics has been previously validated in silico. It accounts for valve dynamics using a second order differential equation to simulate the physiological opening valve law. This second order equation is based on output heart signals and is really difficult to bind with anatomical or physiological parameters, making this model difficult to interpret and to particularise to pathological situations.On the other hand, a simple non-linear rotational spring model implemented to model the motion of mitral valve, located between the left atrium and ventricle has been validated on a literature dataset. A measured pressure difference curve was used as the input into the model, which represents an applied torque to the valve chords. Various damping and hysteresis states were investigated to find a model that best matches reported animal data of chord movement during a heartbeat. This model is based on simple physiological behavior modeling, defining parameters linked with physiological or anatomical data.This research describes a new closed-loop CVS model corresponding to the integration of the simple non-linear rotational spring model to describe the progressive aperture of the mitral valve in the minimal cardiovascular system closed loop model. This new model is proved to fit static and dynamic heart behaviour.

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Mitral valve motion assessed by high-speed video camera in isolated swine heart

Abstract: The present study revealed the integrated movement of the mitral leaflets, chords and annulus, as well as the impact of altered preload.

Cited by 20 publications

References 22 publications

Geometrical orifice area compared to effective orifice area of valvular mitral bioprosthesis:in vitrostudy

Geometrical orifice area compared to effective orifice area of valvular mitral bioprosthesis:in vitrostudy

Mathematical model of the mitral valve and the cardiovascular system Application for studying and monitoring valvular pathologies

Structural model of the mitral valve included in a cardiovascular closed loop model. Static and dynamic validation

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