Mixed-ligand copper(ii) Schiff base complexes: the vital role of co-ligands in DNA/protein interactions and cytotoxicity

Abstract

Four new mixed-ligand copper(ii) complexes display an antibacterial mechanism of cell death via cell-wall rupture and cytotoxicity via apoptotic cell death.

Investigation of DNA‐Binding Activities of Zinc(II) and Cobalt(II) Phthalocyanine Compounds with 3,4,5‐Trimethoxybenzyloxy Substituents

“…In the absence of CT‐DNA, Pc4 and Pc5 had a couple of waves with the cathodic (EPc) and anodic peak potential (EPa) being −0.55 V (EPc) and −0.71, and 0.61 V (EPa) for Pc4 in Figure (red line), and −0.34 V, 0.69 V (EPc) and −0.5, 0.1 and 0.9 V (Epa) for Pc5 in Figure (red Line)), respectively. In the presence of CT‐DNA, after the addition of CT‐DNA to Pc4 andd Pc5 , the cyclic voltammetric peak currents apparently decreased, which is an indicator of the interaction between the compounds and CT‐DNA . Decrease in the voltammetric currents in the presence of CT‐DNA may be a sign of low diffusion of Pc4 and Pc5 that were binding to CT‐DNA.…”

Isolation and Characterization of Different Homometallic and Heterobimetallic Complexes of Nickel and Zinc Ions by Controlling Molar Ratios and Solvents

“…The lower energy band appearing in the range of 280–310 nm is due to π–π* transition in the benzene ring of the ligands. However, absorption bands appearing in the region of 350–380 nm may be attributed to the LMCT , . the three bands observed in the UV/Vis spectra exhibit slight shift in wavelength in different solvents due to varying degree of solute‐solvent interactions.…”

“…However, absorption bands appearing in the region of 350-380 nm may be attributed to the LMCT. [41,42] the three bands observed in the UV/Vis spectra exhibit slight shift in wavelength in different solvents due to varying degree of solute-solvent interactions. The absorption peaks in the polar coordinating solvents (e.g.…”

A Series of Umbrella‐Shape Copper‐Lanthanides Based Mixed Metallic Coordination Complexes

“…The absorption band appearing in the range of 250–320 nm can be attributed to π‐π* transition in the benzene ring of the ligands. However, absorption bands observed in the region of 350–380 nm may be due to the LMCT …”