2005
DOI: 10.1016/j.nano.2005.01.002
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Modeling and characterization of a nanoliter drug-delivery MEMS micropump with circular bossed membrane

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Cited by 46 publications
(20 citation statements)
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“…The results showed that this micropump can provide the large backpressure and the high flow rate. Yih et al (2005) investigated a drug delivery micropump with a circular-bossed membrane and a cantilever valve to improve the flow rate. The analysis and simulation showed that the circular-bossed membrane can generate a larger drawing and pumping force, which is helpful in improving the flow rate.…”
Section: Introductionmentioning
confidence: 99%
“…The results showed that this micropump can provide the large backpressure and the high flow rate. Yih et al (2005) investigated a drug delivery micropump with a circular-bossed membrane and a cantilever valve to improve the flow rate. The analysis and simulation showed that the circular-bossed membrane can generate a larger drawing and pumping force, which is helpful in improving the flow rate.…”
Section: Introductionmentioning
confidence: 99%
“…No commercial development has been reported so far. As miniaturization continues to nanoscale, a microelectromechanical systems micropump with circular bossed membrane designed for nanoliter drug delivery has been characterized [10].…”
Section: Drug Delivery Device Based On Microfluidicsmentioning
confidence: 99%
“…Contemporary trends in pharmaceutical product development that are relevant to DDS are listed in Table 1. 10. Drug delivery technologies have become an important part of the biopharmaceutical industry.…”
mentioning
confidence: 99%
“…This is even more true with micro components as it is more difficult and requires accurate specialized equipment to make measurements and analysis on a small valve than on a macro one. Fluidic models are generally finite-element models (FEM) in the literature [5,6,7,8] where either the deformation of the moving part is computed by FEM, or the fluid flow is computed by FEM, or both as the situation involves complex fluid-structure interaction. A few approximate analytical models have been developed but they are far from reality, as in [9] where the authors neglect the entrance and exit effects on the valve and assume that a Poiseuille flow-profile prevails over the full length of the gap.…”
Section: Introductionmentioning
confidence: 99%