The global transformation of employment is a comprehensive process that changes the principles of market relations and defines the interstate commonality of requirements for the use of labor potential. In case of inconsistency of the global transformation of employment with national peculiarities, the phenomenon of global-local polarization occurs. The labor markets of countries are increasingly affected by global transformational changes, the main factors of which are humanization, dynamic scientific and technological progress, intellectualization, development of the society and the knowledge economy, the appearance of the digital economy, demographic processes, increasing resource mobility, a focus on sustainable development goals, high competition in labor markets, economic growth. Each factor causes specific changes in the labor markets with the appearance of new spheres, forms, standards, employment conditions, features of protection, spatial organization and regulation.