Modelling and analysis of the effects of malnutrition in the spread of cholera

Hove-Musekwa, Senelani D.; Nyabadza, Farai; Chiyaka, Christinah; Das, Prasenjit; Tripathi, Agraj; Mukandavire, Zindoga

doi:10.1016/j.mcm.2010.11.060

Cited by 71 publications

(35 citation statements)

References 30 publications

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“…The ratio of the relative change in a variable to that in a parameter is an index of the sensitivity of the variable to that parameter (26). Sensitivity analysis of the parameters of model Eq.…”

Section: Methods and Resultsmentioning

confidence: 99%

Modeling huanglongbing transmission within a citrus tree

Chiyaka

Singer

Halbert

et al. 2012

Proc. Natl. Acad. Sci. U.S.A.

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100

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The citrus disease huanglongbing (HLB), associated with an uncultured bacterial pathogen, is threatening the citrus industry worldwide. A mathematical model of the transmission of HLB between its psyllid vector and citrus host has been developed to characterize the dynamics of the vector and disease development, focusing on the spread of the pathogen from flush to flush (a newly developing cluster of very young leaves on the expanding terminal end of a shoot) within a tree. This approach differs from that of prior models for vector-transmitted plant diseases where the entire plant is the unit of analysis. Dynamics of vector and host populations are simulated realistically as the flush population approaches complete infection. Model analysis indicates that vector activity is essential for initial infection but is not necessary for continued infection because infection can occur from flush to flush through internal movement in the tree. Flush production, withintree spread, and latent period are the most important parameters influencing HLB development. The model shows that the effect of spraying of psyllids depends on time of initial spraying, frequency, and efficacy of the insecticides. Similarly, effects of removal of symptomatic flush depend on the frequency of removal and the time of initiation of this practice since the start of the epidemic. Within-tree resistance to spread, possibly affected by inherent or induced resistance, is a major factor affecting epidemic development, supporting the notion that alternate routes of transmission besides that by the vector can be important for epidemic development.greening | Candidatus Liberibacter asiaticus | Diaphorina citri

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Section: Methods and Resultsmentioning

confidence: 99%

Modeling huanglongbing transmission within a citrus tree

Chiyaka

Singer

Halbert

et al. 2012

Proc. Natl. Acad. Sci. U.S.A.

Self Cite

100

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“…Waterborne diseases such as cholera remain a major public health problem in developing countries, where outbreaks continue to occur and are intensely interconnected with poverty, malnutrition and poor sanitation [1,2]. Approximately 700,000 children die due to dehydration every year from diarrhea caused by unsafe water [3].…”

Section: Introductionmentioning

confidence: 99%

“…Apart from impoverished countries, low SEC individuals can also be found in places such as refugee camps, areas devastated by war, famine or natural disasters. While everyone is susceptible to waterborne diseases, individuals in low SECs are likely to be more vulnerable to these diseases [1,9] due to the lack of access to a clean water source.…”

Section: Introductionmentioning

confidence: 99%

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Analysis of a waterborne disease model with socioeconomic classes

Collins

Robertson

Govinder

2015

Mathematical Biosciences

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“…The most common cause of live harbor seal strandings in central California during the last ten years was malnutrition (52%) [16]. Malnourished individuals may be more susceptible to enteric pathogens [44]. To better understand impacts of enteric pathogens on the health of harbor seals, enumerating these pathogens in healthy and stranded seals is warranted [10,16,32,48,51].…”

Section: Introductionmentioning

confidence: 99%