2008
DOI: 10.1016/j.intimp.2008.01.030
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Modulating effects of fumonisin B1 and ochratoxin A on leukocytes and messenger cytokines of the human immune system

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Cited by 28 publications
(13 citation statements)
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“…For blood hematology, only a reduction in neutrophil numbers was noticed in FBexposed piglets. This observation is in relation with the reduced viability measured in human neutrophils exposed in vitro to this toxin [31]. For blood biochemistry, there was a decrease in albumin concentration in DON-exposed animals and an increase in creatinin concentration in FB-exposed piglets in accordance with previously published studies [18,20,32,33].…”
Section: Discussionsupporting
confidence: 91%
“…For blood hematology, only a reduction in neutrophil numbers was noticed in FBexposed piglets. This observation is in relation with the reduced viability measured in human neutrophils exposed in vitro to this toxin [31]. For blood biochemistry, there was a decrease in albumin concentration in DON-exposed animals and an increase in creatinin concentration in FB-exposed piglets in accordance with previously published studies [18,20,32,33].…”
Section: Discussionsupporting
confidence: 91%
“…We observed that OTA caused more damage in the cell membrane of lymphocytes than in the mitochondrial respiratory chain. Odhav et al (2008) also reported cell membrane disruption and damage to cytoplasmic organelles on human leukocytes exposed to OTA (50 g/mL).…”
Section: Discussionmentioning
confidence: 84%
“…Problems related to these mycotoxins are almost exclusively associated with the consumption of contaminated maize or products made from maize. Fumonisins are suspected risk factors for esophageal and liver cancers, neural tube defects and cardiovascular problems in populations consuming relatively large amounts of food made with the contaminated matrix (IARC, 2002;Odhav, Adam, & Bhoola, 2008;Wang et al, 2005).…”
Section: Toxic Effects On Human Healthmentioning
confidence: 99%