Molecular characterizations of Cryptosporidium, Giardia, and Enterocytozoon in humans in Kaduna State, Nigeria

Maikai, B.V.; Umoh, J. U.; Lawal, Idris Alao; Kudi, A. C.; Ejembi, Clara Ladi; Xiao, Lihua

doi:10.1016/j.exppara.2012.05.011

Cited by 59 publications

(40 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4,[11][12][13][14] According to WHO, diarrhea is regarded as the second highest cause of morbidity and mortality among the children in developing countries, 1 for which cryptosporidiosis and rotavirus are the most common parasitic and viral cause for gastroenteritis worldwide. 2 Comparing with studies carried out in other Iraqi provinces, our record was much lower than that reported by 11,12 in children aged less than three years old in Erbil and Sulaimani, respectively. However this finding was higher than that reported in some surrounding countries, Iran (4.6%) 13 and Kuwait (3.4%).…”

Section: Discussioncontrasting

confidence: 53%

“…It is also the most common cause of waterborne disease around the world. 2 Successful management and prevention of this emerging disease requires knowledge of the diversity of species causing human disease and their zoonotic source. It commonly appears as intestinal infection in acquired immunedeficiency syndrome (AIDS) patients causing fatal diarrheal illness.…”

mentioning

confidence: 99%

See 1 more Smart Citation

<em>Cryptosporidium</em> spp. and rotavirus gastroenteritis and change of incidence after rotavirus vaccination among children in Raparin Pediatrics Hospital, Erbil, Iraq

Azeez¹,

Alsakee

2017

Med J Indones

View full text Add to dashboard Cite

ABSTRAK (11,7%). Puncak infeksi terjadi selama musim semi 9 (65,9% vs 14,1%, p<0,05). ,5%). Tingkat deteksi rotavirus (32,0%) sedikit lebih tinggi pada laki-laki (34,4% vs 30,0%) dan anak usia 1 sampai 3 tahun (39,3%). Tingkat deteksi tertinggi (38,6%) terjadi selama musim dingin (Januari dan Februari). Infeksi lebih tinggi bermakna pada anak yang tidak divaksin Kesimpulan: Insidens cryptosporidiosis mengalami penurunan tetapi gastroenteritis akibat rotavirus cukup banyak terjadi pada anak-anak di Erbil. Vaksin rotavirus menurunkan insidens infeksiakibat rotavirus secara bermakna. ABSTRACTBackground: Watery diarrhea is the most common medical problem among infants and young children, caused by different microbial etiology including Cryptosporidium spp. and rotavirus, which are usually misdiagnosed in conventional stool test. This study aimed to investigate the incidence of Cryptosporidium and rotavirus gastroenteritis among children in Erbil as well as evaluate the efficacy of rotavirus vaccination procedure applied in Erbil.

show abstract

Section: Discussioncontrasting

confidence: 53%

mentioning

confidence: 99%

<em>Cryptosporidium</em> spp. and rotavirus gastroenteritis and change of incidence after rotavirus vaccination among children in Raparin Pediatrics Hospital, Erbil, Iraq

Azeez¹,

Alsakee

2017

Med J Indones

View full text Add to dashboard Cite

show abstract

“…33 In this study, the distribution of E. bieneusi genotypes seems to be different from that identified previously in HAART-naïve HIV patients and children in Nigeria. Compared with the occurrence of common genotypes such as A, D, Type IV, and WL7 in Group 1 in previous studies, 13,34,35 the E. bieneusi genotypes detected in this study mostly belonged to Nig4 and two new genotypes related to Nig4. Because this group of genotypes is very divergent from other known genotype groups and seems to be specific to humans, we have named the new genotype group as Group 6.…”

Section: Discussionmentioning

confidence: 99%

“…Likewise, the C. hominis Id-like subtype family seen in two patients in this study has never been reported in humans in previous studies in Nigeria. 5,6,35,36 Additional studies are required to determine whether some E. bieneusi genotypes and C. hominis subtypes are more common in HIV patients on HAART.…”

Section: Discussionmentioning

confidence: 99%

Unusual Enterocytozoon bieneusi Genotypes and Cryptosporidium hominis Subtypes in HIV-Infected Patients on Highly Active Antiretroviral Therapy

Akinbo

Okaka²,

Omoregie³

et al. 2013

The American Society of Tropical Medicine and Hygiene

Self Cite

View full text Add to dashboard Cite

Abstract. Human immunodeficiency virus (HIV)-infected persons are commonly infected with Cryptosporidium species and Enterocytozoon bieneusi in both developed and developing countries, particularly patients with CD4+ cell counts below 200 cells/μL; 285 HIV-infected patients on highly active antiretroviral therapy (HAART) were enrolled in this study, and both stool and blood specimens were collected from participants. The stool specimens were analyzed and typed for E. bieneusi and Cryptosporidium spp. by polymerase chain reaction (PCR) and DNA sequencing. CD4 count was analyzed using flow cytometry.

show abstract

“…Molecular characterizations of Cryptosporidium spp. in a small number of HIV-infected persons and children in southwestern and mid-western states have provided some information on Cryptosporidium species and subtypes in Nigeria [4,6,[8][9][10][11]. However, no information is available on the species and subtypes circulating in humans in south-eastern Nigeria.…”

Section: Introductionmentioning

confidence: 99%

Cryptosporidium species and subtypes in diarrheal children and HIV-infected persons in Ebonyi and Nsukka, Nigeria

Ukwah

Ezeonu

et al. 2017

J Infect Dev Ctries

Self Cite

View full text Add to dashboard Cite

Introduction: Cryptosporidiosis is a common disease of children and immune-compromised persons. This study evaluated the diversity and distribution of Cryptosporidium species in diarrheal children and HIV-infected persons on highly active antiretroviral therapy (HAART) and those not on HAART. Methodology: A total of 394 fecal specimens were collected from patients attending clinics in Nsukka and Ebonyi, Nigeria. Detection and identification of Cryptosporidium species were conducted by PCR-RFLP of the small subunit (SSU) rRNA gene, whereas subtyping was done by sequence analysis of the 60 kDa glycoprotein (gp60) gene. Results: Twenty-five (6.3%) specimens yielded four Cryptosporidium species, including C. hominis, C. parvum, C. felis, and C. viatorum. C. hominis was the most dominant species with 48.0% occurrence and three identified subtype families: Ia (six specimens), Ib (three specimens), Ie (two specimens), and one un-subtyped species. C. parvum had 44.0% occurrence and two subtype families: IIc (eight specimens) and IIe (three specimens), while C. felis and C. viatorum each had 4.0% occurrence. There were significant differences in Cryptosporidium species distribution between age groups in children and HIV-infected persons, between suburban and urban areas, and between low and high CD4

show abstract

Molecular characterizations of Cryptosporidium, Giardia, and Enterocytozoon in humans in Kaduna State, Nigeria

Cited by 59 publications

References 30 publications

<em>Cryptosporidium</em> spp. and rotavirus gastroenteritis and change of incidence after rotavirus vaccination among children in Raparin Pediatrics Hospital, Erbil, Iraq

<em>Cryptosporidium</em> spp. and rotavirus gastroenteritis and change of incidence after rotavirus vaccination among children in Raparin Pediatrics Hospital, Erbil, Iraq

Unusual Enterocytozoon bieneusi Genotypes and Cryptosporidium hominis Subtypes in HIV-Infected Patients on Highly Active Antiretroviral Therapy

Cryptosporidium species and subtypes in diarrheal children and HIV-infected persons in Ebonyi and Nsukka, Nigeria

Contact Info

Product

Resources

About