Molecular imprinting for bio- and pharmaceutical analysis

Owens, Paul K.

doi:10.1016/s0165-9936(98)00092-2

Cited by 150 publications

(51 citation statements)

References 42 publications

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“…The use of MIPs in CEC has been discussed in specific reviews, [1066][1067][1068][1069][1070][1071] book chapters, 1072,1073 and also in general reviews on the application of molecular imprinting to analytical separations. 987,[1074][1075][1076][1077][1078][1079] Also, reviews on CEC have increasingly highlighted MIPs as interesting novel materials for selective enantiomer separations. [1080][1081][1082][1083][1084][1085][1086][1087][1088][1089][1090][1091][1092] Research into imprint-based CEC separations has to a large extent focused on the development of novel MIP stationary phases within fused silica capillaries.…”

Section: Capillary Electro-chromatographymentioning

confidence: 99%

Molecular imprinting science and technology: a survey of the literature for the years up to and including 2003

Andersson²,

et al. 2006

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Over 1450 references to original papers, reviews and monographs have herein been collected to document the development of molecular imprinting science and technology from the serendipitous discovery of Polyakov in 1931 to recent attempts to implement and understand the principles underlying the technique and its use in a range of application areas. In the presentation of the assembled references, a section presenting reviews and monographs covering the area is followed by papers dealing with fundamental aspects of molecular imprinting and the development of novel polymer formats. Thereafter, literature describing attempts to apply these polymeric materials to a range of application areas is presented.

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Section: Capillary Electro-chromatographymentioning

confidence: 99%

Molecular imprinting science and technology: a survey of the literature for the years up to and including 2003

Andersson²,

et al. 2006

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“…Copyright Chiral imprinted polymers as CSPs also found application in CEC. Several reviews report on recent developments and applications in this field [498][499][500][501][502].…”

Section: Open Tubular Capillariesmentioning

confidence: 99%

Chiral separation by chromatographic and electromigration techniques. A Review

Gübitz

Schmid

2001

Biopharm & Drug Disp

226

135

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This review gives a survey of different chiral separation principles and their use in high-performance liquid chromatography (HPLC), gas chromatography (GC), supercritical fluid chromatography (SFC), thin-layer chromatography (TLC), capillary electrophoresis (CE) and capillary electrochromatography (CEC) highlighting new developments and innovative techniques. The mechanisms of the different separation principles are briefly discussed and some selected applications are shown.

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“…They are very useful materials for isolation and preconcentration of low concentration analytes employing the solid phase extraction (SPE) technique [14][15][16]. Although many papers have been published concerning utilization of MIPs in pharmaceutical science [17][18][19], only a few were devoted to dopamine isolation [20][21][22][23][24]. Recently, two scientific groups have published their results of the evaluation of dopamine imprinted polymers prepared using synthetic methods based on covalent [22] and non-covalent [23] approaches.…”

mentioning

confidence: 99%

Dopamine-Imprinted Polymers: Template-Monomer Interactions, Analysis of Template Removal and Application to Solid Phase Extraction

Luliński

Maciejewska

Bamburowicz-Klimkowska

et al. 2007

Molecules

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A dopamine-imprinted polymer (MIP) was prepared in aqueous methanol solution at 60 o C by free-radical cross-linking polymerization of methacrylic acid in the presence of ethylene glycol dimethacrylate as the cross-linker and dopamine hydrochloride as the template molecule. Its ability to isolate dopamine was evaluated as the basis of a solid phase extraction procedure and compared with that of a non-imprinted polymer (NIP). The binding of dopamine was 84.1% and 29.1% for MIP and NIP, respectively. Various reported post-polymerization treatments to reduce template bleeding were examined. In our case the lowest bleeding was achieved after applying a combined procedure: continuous extraction in a Soxhlet apparatus (CE), followed by microwaveassisted extraction (ME) to a level of 0.061 μg/mL. A simplified model of the templatemonomer complexes allowed rationalization of monomer choice based on the heats of complex formation at a PM3 level of theory.

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Molecular imprinting for bio- and pharmaceutical analysis

Cited by 150 publications

References 42 publications

Molecular imprinting science and technology: a survey of the literature for the years up to and including 2003

Molecular imprinting science and technology: a survey of the literature for the years up to and including 2003

Chiral separation by chromatographic and electromigration techniques. A Review

Dopamine-Imprinted Polymers: Template-Monomer Interactions, Analysis of Template Removal and Application to Solid Phase Extraction

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