Molecularly imprinted polymers with a streamlined mimic for zearalenone analysis

Syntheses of molecularly imprinted polymers: Molecular recognition of cyproheptadine using original print molecules and azatadine as dummy templates

“…Although previous papers demonstrated that DMIP could be used for selective recognition of the original template with good binding properties [14][15][16], these materials are often inferior in terms of selectivity for the target analyte [17,18], losing recognition and extraction capacities for the compound from the matrices. Polymeric particles for selective recognition of CPH using azatadine (AZA) as a dummy template, or CPH as an original print molecule, and MAA and AA as monomers, by bulk polymerization were synthesized and characterized by surface electron microscopy (SEM), binding properties to CPH, and swelling behaviour.…”

Comparing Corn Stover and Switchgrass Biochar: Characterization and Sorption Properties

“…Referring to Table 1, SB had nitrogen content nearly twice that of the CSB, so this may be reflected qualitatively in the spectra here. Amine functional groups have been shown to have strong binding activity to ZEN (Urraca, Marazuela, Merino, Orellana, & Moreno-Bondi, 2006), and should also bind E1 and E2, since all three are weak acids and capable of hydrogen bonding. The peaks near 1590 cm -1 may also represent aromatic C=C, common in biochar.…”

Molecular imprinted polymers as synthetic receptors for the analysis of myco- and phyco-toxins

“…In a different approach, Urraca et al 33 used the cyclododecanoyl ester of resorcilic acid as a mimic template to prepare imprinted polymers based on allylpiperazine as functional monomer, trimethylolpropan trimethacrylate as cross-linker and acetonitrile as porogenic solvent. As previously described, the choice of cyclododecanoyl resorcilate (15) as mimic template was made on the basis of its commercial availability and its resemblance to ZON in terms of size, shape and functionality, aiming to preserve the resorcilic sub-structure directly involved in the hydrogen bond interaction with functional monomers.…”

“…As a consequence, in many cases, structural differences between the analyte and the mimic template are significant, and similarity between molecules remains confined to the overall molecular shape and the preservation of substituents able to form non-covalent interactions with the binding sites. For example, Urraca et al 12,33 prepared an imprinted polymer for the isolation of the mycotoxin zearalenone (7) and its main metabolites from corn extracts using a mimic template obtained from the esterification of resorcilic acid with cyclododecanol (15). In this case, the choice of the mimic template was due not only to the necessity to avoid column bleeding during the MISPE process, but also to the toxicity of zearalenone, which made it unsuitable as a template molecule.…”