Monte Carlo study on effective source to surface distance for electron beams from a mobile dedicated IORT accelerator

Aghdam, Mir Rashid Hosseini; Baghani, Hamid Reza; Mahdavi, Seied Rabi; Aghamiri, Seyed Mahmoud Reza; Akbari, Mohammad Esmail

doi:10.1017/s1460396916000455

Cited by 14 publications

(3 citation statements)

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“…The output beam has a 3 mm diameter and is collimated by the sterilisable cylindrical PMMA applicator through the hard-docking system. Employed applicators are cylindrical tubes with 5 mm thickness and 60 cm length 41 . The diameter of these applicators changes between 3 and 10 cm (3, 4, 5, 6, 7, 8 and 10 cm), and their base angle changes from 0° to 45° (0°, 15°, 30° and 45°) 42 .…”

Section: Resultsmentioning

confidence: 99%

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Breast intraoperative radiotherapy: a review of available modalities, dedicated machines and treatment procedure

2018

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BackgroundBreast intraoperative radiotherapy (IORT) is a partial irradiation technique that delivers a single fraction of radiation dose to the tumour bed during surgery. The use of this technique is increasing (especially in the Middle East), and therefore, it is essential to have a comprehensive approach to this treatment modality. The aim of this study is to conduct a literature review on available IORT modalities during breast irradiation as well as dedicated IORT machines and associated treatment procedures. The main IORT trials and corresponding clinical outcomes are also studied.Materials and MethodsA computerised search was performed through MEDLINE, PubMed, PubMed Central, ISI web of knowledge and reference list of related articles.ResultsIORT is now feasible through using two main modalities, including low-kilovolt IORT and intraoperative electron radiotherapy (IOERT). The dedicated machines employed and treatment procedure for mentioned modalities are quite different. The outcomes of implemented clinical trials showed that IORT is not inferior to external beam radiotherapy (EBRT) in specifically selected and well-informed patients and can be considered as an alternative to EBRT.ConclusionAlthough the clinical outcomes of introduced IORT methods are comparable, but based on the review results, it could be said that IOERT is the most effective technical method, in view of the treatment time and dose uniformity concepts. The popularity of IORT is mainly due to the distinguished obtained results during breast cancer treatment. Despite the presence of some technical challenges, it is expected that the IORT technique will become more widespread in the immediate future.

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Section: Resultsmentioning

confidence: 99%

“…Employed applicators are cylindrical tubes with 5 mm thickness and 60 cm length. 41 The diameter of these applicators changes between 3 and 10 cm (3, 4, 5, 6, 7, 8 and 10 cm), and their base angle changes from 0°to 45°(0°, 15°, 30°a nd 45°). 42 The length of employed applicators is equal to 60 cm.…”

Section: Liacmentioning

confidence: 99%

Breast intraoperative radiotherapy: a review of available modalities, dedicated machines and treatment procedure

2018

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“…The gamma index calculations were performed by Gnuplot software (version 4.4 patch level 3; Geek net Inc., Fairfax, VA, USA) using its gamma index executive file. 17…”

Section: Simulationmentioning

confidence: 99%

Evaluating the radiation contamination dose around a high dose per pulse intraoperative radiotherapy accelerator: a Monte Carlo study

et al. 2020

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Aim: In this study, the radiation contamination dose (RCD) for different combinations of electron energy/distance, applicator and radius around the light intraoperative accelerator (LIAC), a high dose per pulse dedicated intraoperative electron radiotherapy machine, has been estimated. Being aware about the amount of RCDs is highly recommended for linear medical electron accelerators. Methods and methods: Monte Carlo Nuclear Particles (MCNP) code was used to simulate the LIAC® head and calculate RCDs. Experimental RCDs measurements were also done by Advanced Markus chamber inside a MP3-XS water phantom. Relative differences of simulations and measurements were calculated. Result: RCD reduction by distance from the machine follows the inverse-square law, as expected. The RCD was decreased by increasing angle from applicator walls opposed to the electron beam direction. The maximum differences between the simulation and measurement results were lower than 3%. Conclusions: The RCD is strongly dependent on electron beam energy, applicator size and distance from the accelerator head. Agreement between the MCNP results and ionometric dosimetry confirms the applicability of this simulation code in modelling the intraoperative electron beam and obtaining the dosimetric parameters. The RCD is a parameter that would restrict working with LIAC in an unshielded operative room.

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Monte Carlo-based determination of radiation leakage dose around a dedicated IOERT accelerator

Baghani

Aghdam

Robatjazi

et al. 2019

Radiat Environ Biophys

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Monte Carlo study on effective source to surface distance for electron beams from a mobile dedicated IORT accelerator

Cited by 14 publications

References 20 publications

Breast intraoperative radiotherapy: a review of available modalities, dedicated machines and treatment procedure

Breast intraoperative radiotherapy: a review of available modalities, dedicated machines and treatment procedure

Evaluating the radiation contamination dose around a high dose per pulse intraoperative radiotherapy accelerator: a Monte Carlo study

Monte Carlo-based determination of radiation leakage dose around a dedicated IOERT accelerator

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