Morbidity in a large cohort study of children born to mothers exposed to radiation from chernobyl

Abstract

Reproductive health was reviewed in four oblasts of the Republic of Belarus that were either heavily exposed (Mogilev and Gomel) or lightly exposed (Brest and Vitebsk) to ionizing radiation after the meltdown of a nuclear reactor in Chernobyl. A retrospective analysis was conducted on pregnancies occurring between January 1, 1982, and December 31,1990, and a comparison of results was made between pregnancy outcomes prior to and after the meltdown for individuals residing in heavily exposed and lightly exposed oblasts. Pregnant women who resided in heavily exposed oblasts appeared to be at risk for development of toxemia, renal insufficiency and anemia. Neonates born in heavily contaminated areas were apparently at risk for development of anemia and congenital malformations and perinatal death. In addition, a cohort of 757 neonates, 0-18 months old, with a normal physical examination, was identified for laboratory analysis of hematological, immunological, endocrinological and nutritional status. Decreased levels of copper and zinc were documented in erythrocytes from neonates from heavily contaminated oblasts, findings that may he related more to inadequate nutrition than to radiation exposure. Increased absolute "null" lymphocyte number and diminished absolute T lymphocyte number with a reduction in the "helper" (i.e.,

The effect of ionising radiation on testosterone binding globulin characteristics: Correction of the protein' parameters by lipid polyene complexes of fungusLaetiporus sulfureus

“…Teenagers and children (especially 57 years old) became the most afflicted (Lomat et al 1997). Consequent hypothyroid statuses caused increases in psychosomatic disorders, delays in sexual, intellectual and age progress in victims and additional (through injured mothers) negative contributions to the birth rate of 2,500 newborns annually registered with various deviations, e.g., 4500 pregnancies per year interrupted because of pathologies (Nesterenko et al 1993, Petrova et al 1997, Yablokov et al 2006. Among congenital malformations the number of disturbances in genital organs increased most rapidly (Kulakov et al 2001).…”

7. Mortality after the Chernobyl Catastrophe

“…An analysis of pregnancy outcomes before and after the catastrophe (1982 to 1990) revealed that neonatal mortality increased in Gomel and Mogilev, the two most highly contaminated regions of Belarus (Petrova et al, 1997).…”

Chronic Renal Disorder after a Nuclear Crisis: A Brief Review

“…Indeed, the pregnant women are the vulnerable group to develop renal deficiency in nuclear crisis. 12,13 Increased renal problem and deterioration of renal function in the pregnant exposed to nuclear crisis are reported. 12,13 However, the problem might extend to their offsprings.…”

“…12,13 Increased renal problem and deterioration of renal function in the pregnant exposed to nuclear crisis are reported. 12,13 However, the problem might extend to their offsprings. 12 In an animal study, Tissandie et al 14 concluded that "early exposure to post-accidental doses of 137 Cs induces the alteration of vitamin D metabolism, associated with a dysregulation of mineral homeostasis."…”