Morganella as a cause of ophthalmia neonatorum

Ward, Michael F.; Olson, Daniel J.; Taggart, Michael; Grace, Sara

doi:10.1016/j.jaapos.2017.08.012

Cited by 4 publications

(3 citation statements)

References 10 publications

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“…morganii is an unusual infectious agent in the pediatric age group, especially in the neonatal period [2,7]. In addition to neonatal sepsis, it can rarely cause meningitis, pneumonia [5,6], necrotizing fasciitis, ventriculitis, cerebral abscesses, fetal death [6], and ocular infections [8].…”

Section: Introductionmentioning

confidence: 99%

Morganella morganii: A Rare Cause of Early-Onset Neonatal Sepsis

Gameiro,

Botelho,

Martins

et al. 2023

Cureus

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Morganella morganii is an opportunistic Gram-negative bacillus commonly found in the human gastrointestinal tract and the environment. In adults, it is often associated with nosocomial infections, primarily surgical wound infections, urinary tract infections, and hepatobiliary infections. It is a rare cause of early-onset neonatal sepsis, with fewer than 15 reported cases in the literature. The authors aim to present a case of a low birth weight preterm born at 28 weeks' gestation, who developed early-onset neonatal sepsis due to M. morganii. We successfully treated the infection using a combination of thirdgeneration cephalosporin and aminoglycoside, and in this report, we explain the rationale behind employing this antibiotic therapy.

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Section: Introductionmentioning

confidence: 99%

Morganella morganii: A Rare Cause of Early-Onset Neonatal Sepsis

Gameiro,

Botelho,

Martins

et al. 2023

Cureus

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“…5,6 Current evidence on ON focuses heavily on preventative measures, although data on ON management when presenting to the emergency department (ED) is sparse and mainly based on case reports and surveys. [7][8][9][10][11] Existing guidelines only address neonates born to mothers with suspected sexually transmitted infections in the immediate postdelivery period. 1 Part of the issue is the lack of data for clinical outcomes among neonates with ON.…”

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confidence: 99%

“…Few case reports have been published in the past 15 years of neonates with ON presenting specifically to the ED [10][11][12] or to a health care facility. 8,9,13 In addition to limited data reporting mostly cases with complications, there was also significant variation in the management strategies reported for the different case reports: investigations ranging from conjunctival swabs 5 to full septic workup 6 as well as disposition plan with outpatient topical antibiotics to hospitalization with intravenous (IV) antibiotics and subspecialist consultations.…”

mentioning

confidence: 99%

Is Ophthalmia Neonatorum Associated With Invasive Bacterial Infection? A Single-Center Retrospective Study

St-Onge-St-Hilaire,

Boutin,

Gravel

2023

Pediatr Emer Care

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Objective Ophthalmia neonatorum (ON) is a conjunctivitis occurring in neonates and can be caused by multiple bacterial pathogens. The risk of invasive bacterial infection (IBI) in neonates with ON is poorly known. Our objectives were to document the association of ON with IBI in term neonates and to investigate practice variation. Methods This was a retrospective observational study of all neonates who presented to a single emergency department (ED) between January 2018 and December 2019. Participants were all children with a final diagnosis of ON according to the treating physician as registered in the ED computerized database. Newborns with craniofacial malformations and premature infants were excluded. The primary outcome was IBI as defined by growth of any bacterial pathogen in the blood or cerebrospinal fluid. Perinatal risk factors, ED visit details (symptoms on presentation, management, and treatment plan) as well as complications (ocular morbidity, death, and unscheduled return visits) were collected. Data were analyzed using descriptive statistics. Results Fifty-two term neonates were included. There were no cases of IBI associated with ON (0%; 95% confidence interval [CI], 0%–6.9%). Six ocular bacterial infections were identified, one of which was Chlamydia trachomatis. Although there were no IBIs, ocular complications, deaths, or unscheduled return visits to the ED, there was a wide variation in physician's management of ON. Physicians ordered investigations in 49% (95% CI, 34%–62%) of neonates, prescribed antibiotics to 87% (95% CI, 74%–94%), and involved specialists in 39% (95% CI, 27%–52%) of cases. Conclusions Emergency department presentations of term neonates with ON are associated with a low risk of IBI. A better understanding of the current practice variation is needed to inform clinical guidelines for the management of neonates with ON presenting to the ED.

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Ringing bells: Morganella morganii fights for recognition

Bandy

2020

Public Health

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Morganella as a cause of ophthalmia neonatorum

Cited by 4 publications

References 10 publications

Morganella morganii: A Rare Cause of Early-Onset Neonatal Sepsis

Morganella morganii: A Rare Cause of Early-Onset Neonatal Sepsis

Is Ophthalmia Neonatorum Associated With Invasive Bacterial Infection? A Single-Center Retrospective Study

Ringing bells: Morganella morganii fights for recognition

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