Morpheaform facial basal cell carcinoma – a 16‐year experience in an Asian center

Radiotherapy of morphea‐type basal cell carcinoma: results in 127 cases

“…This is mainly due to the poor definition of the borders of the lesion (‘iceberg epithelioma’) and to the diagnostic delay caused by its slow growth and the often deceptive clinical appearance. Such features of the neoplasm influence therapeutic results so that they appear worse than those obtained in the other forms of BCCs . As far as radiotherapy is concerned, the opinions about its role in the treatment of MBCCs are very discordant in the literature.…”

“…Such features of the neoplasm influence therapeutic results so that they appear worse than those obtained in the other forms of BCCs. 4,7,9,13,14 As far as radiotherapy is concerned, the opinions about its role in the treatment of MBCCs are very discordant in the literature. According to some Authors, [15][16][17] MBCCs are radioresistant.…”

“…On the other side, also literature data about the treatment of MBCCs with therapies different from the radiological one are scanty and often based on very few cases, 4,8,9,13,14,18 yielding information scarcely useful for a comparison with our results after RT. They mostly regard surgical treatment: a series of 83 cases 14 had relapses in 20%.…”

“…From our previous study on radiotherapy (RT) of MBCCs, many years have passed by and several reports have been published debating about the therapeutic choice, with surgery, and in particular Mohs’ surgery, playing the major role . In our knowledge, only one study about RT of BCCs, where the question of MBCCs is widely discussed, has been reported in the recent literature.…”

“…From our previous study 2 on radiotherapy (RT) of MBCCs, many years have passed by and several reports have been published debating about the therapeutic choice, with surgery, and in particular Mohs' surgery, playing the major role. [3][4][5][6][7][8][9] In our knowledge, only one study about RT of BCCs, where the question of MBCCs is widely discussed, has been reported 10 in the recent literature. The problem of the therapeutic response of MBCC, lower than that of the other types of BCC, has not been solved for now, as well as the role of RT in the therapeutic strategy of MBCC is still to be defined.…”