Morphofunctional evaluation of buccopharyngeal space using three-dimensional cone-beam computed tomography (3D-CBCT)

Acrylic resins are frequently used in dentistry for the removable partial or complete denture but, epidemiological studies report that approximately 70% of removable denture wearers suffer from denture stomatitis. Silver nanoparticles (AgNps) incorporation aims to avoid or at least to decrease the microbial colonization over dental materials, but their influence on the mechanical features is still not very well known. A total of 100 heat curing and 100 of self-curing acrylic resin samples were made, and divided into three groups for both resins (ten for each), according to the concentration of AgNPs solution (5%, 10%, and 20% vol.) incorporated into the monomer. One control group without AgNPs for each resin was prepared, as well. The dimensions of the used AgNPs, were 20, 40 and 60 nm. The structural changes were analyzed with Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM). The thermal behavior was evaluated through Differential Scanning Calorimetry (DSC). The results demonstrated that AgNPs incorporation doesn�t induce significant structural and thermal changes in dental resins.

Section: Resultsmentioning

confidence: 99%

Structural and Thermal Changes in Dental Resins Enriched with Silver Nanoparticles

Vițalariu¹,

Tatarciuc²,

Luca³

et al. 2019

“…Research on colorectal carcinomas using immunohistochemical techniques with Ki-67 protein is simple and relatively easy to apply. The results are reproducible using the MIB 1 antibody with which excellent stains can be obtained, even on the classically fixed paraffin blocks [29][30][31][32][33][34][35]. Ki-67 expression is high in non-mucosal adenocarcinomas, highly or moderate differentiated, and is low in those that are low differentiated with mucin secretion.…”

Section: Resultsmentioning

confidence: 94%

Anatomical and Immunohistochemical Evaluation of Colorectal Cancer

Hînganu¹,

Stan²,

Ciupilan³

et al. 2019

Colorectal cancer is a malignant disease with high morbidity and mortality. Ki-67 is a marker of cell proliferation associated with a low survival in colorectal cancer patients. Its expression is increased in patients with Dukes C or D colorectal cancer versus those in stage A or B. The purpose of the study is to evaluate the immunohistochemical expression of the Ki-67 marker in colorectal adenocarcinomas. The study was performed on a group of 28 patients diagnosed with rectal cancer. We made the histopathological and immunohistochemical evaluation of patients in the study group. The evaluation was performed on the sections stained with hematoxylin-eosin, and for mucinous forms, on sections stained with alcian blue. The topography of the Ki-67 reaction is strictly nuclear, evident in areas with intense proliferative activity. In cases with a strong positive response to Ki-67, the prognosis is worse, with invasion of the perirectal tissues and metastases. The lack of Ki-67 expression in nearby neoplastic tissues suggests that cancerous tissue proliferates in a pathway that it is not correlated with adjacent tissues. The Ki-67 could be useful in the prognosis of patients with colorectal cancer.

“…Anti-inflammator y enzymes favor pancreatic dissolution and excretion, decrease the degree of pancreatic fibrosis and accelerate drug diffusion to the lesion [11][12][13][14]. Currently, new formulations of antiinflammatory enzymes are successfully prepared to improve their functional characteristics, pharmacokinetic properties and anti-inflammatory efficacy.…”

Section: Resultsmentioning

confidence: 99%

Enzymatic Treatment of Chronic Pancreatitis

Grigorovici¹,

Andronic²,

Hînganu³

et al. 2019

The treatment of chronic pancreatitis consists of conservative and surgical treatment. The current development of interventional endoscopy techniques links the two above-mentioned treatments, offering less invasive solutions. In the treatment of chronic pancreatitis, a progressive approach is needed. Establishing any type of treatment is useless if the patient does not follow the recommendation to mainatin a proper diet. The study was conducted on a group of 61 patientshospitalized and operated for chronic forms of pancreatitis. Pancreatic insufficiency due to chronic pancreatitis is not a simple enzymatic deficiency, but an interactive complex of secretory, motor and endocrine functional disorders. Therefore, developing drug therapy will require not only the simple administration of enzymes in the intestine but also the restoration of the integrity of disruptive digestive functions.