Mortality among older adults after a traumatic brain injury: A meta-analysis

Abstract

These mortality rates associated with moderate and severe injuries may be attributed to complications, chronic disease prevalence, conservative management techniques or the consequences of biological ageing.

Outcome and Surgical Management for Geriatric Traumatic Brain Injury: Analysis of 888 Cases Registered in the Japan Neurotrauma Data Bank

“…In several other studies, patients with TBI who require ICP monitoring have low GCS scores and their outcome has been found to be poor (22,24,26). In accord with those studies, our result indicates that ICP monitoring might actually be harmful and unnecessary for elderly TBI patients 65 years of age and older.…”

Trauma Team Activation for Geriatric Trauma at a Level II Trauma Center: Are the Elderly Under-triaged?

“…32 When comparing age stratified TBI patients, geriatrics have nearly a 75% higher mortality rate than their younger counterparts. [32][33][34][35][36] Further analysis demonstrates GCS as a precarious predictive factor in determining outcomes in the geriatric population. For example, a 60% mortality rate was highlighted in Table 2 in those patients with head trauma and a GCS ≤ 12 (ISS was 21.5; well above the major trauma value of 15).…”

Initial GCS and laboratory findings of patients with TBI are associated with the GOSE and mortality rate at one year

“…This result was confirmed by a meta-analysis study including 24 studies, which showed that the mortality is significantly different between patients with higher GCS and patients with lower initial GCS. 25 Brain edema is an important issue in management of patients with TBI and has complex cellular and molecular mechanisms. Sodium-water balance plays an important role in its occurrence.…”