Mortality among organophosphate poisoning patients presenting with low Glasgow coma scale score at A Tertiary Care Hospital.

Abstract

This study is designed to assess the mortality in OPP patients with low GCS scores. Study Design: Cross Sectional study. Setting: Jinnah Postgraduate Medical Center. Period: From 1st February 2018 to 31st August 2018. Material & Methods: Included patients with low GCS, both genders and age of 18-60 years diagnosed with OPP. Their GCS was calculated and the outcome was determined in terms of mortality. Results: Out of 70 patients, the mean age was 35.2+16.5 years with the majority (62.9%) <30 years. 62.9% of these were males. Most (57.1%) of them presented after ingestion of <15mL of OP, 60% had the poisoning for >60 minutes, and the majority (74.3%) had taken it orally. When the GCS was computed, 81.40% had that of >5, while the mean came out to be 6.64 ±1.43. The mortality rate here was 17.10%. Conclusion: GCS toll can be a helpful and practical tool in assessing the mortality among the patients of OPP. However, because of the limited literature on the subject further studies are recommended to improve its validity.

Clinical profile and outcome of acute organophosphate poisoning in children of Upper Egypt: a cross-sectional study

“…In general, pediatric studies report frequency of unintentional ingestions and tend to have a lower mortality than adult studies. As reported by Reddy et al [20], and Ali et al [21] studies, adults are exposed to higher doses with intentional ingestions so carry higher mortality. The mean time to presentation from toxic exposure to hospital presentation in our study was significantly higher in non survivors.…”