Motor and sensory polyneuritis with distal conduction failure as uncommon complication of an acute Rickettsia conorii infection

Spengos, Konstantinos; Stouraitis, Georgios; Voumvourakis, Konstantinos; Karandreas, Nikolaos

doi:10.1016/j.jns.2005.03.045

Cited by 6 publications

(1 citation statement)

References 11 publications

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“…In recent years, atypical and serious life-threatening presentations of MSF in Mediterranean countries were reported, with cardiac symptoms (ectasia of the coronary arteries, myocarditis, and atrial fibrillation) (231-233), ocular symptoms (uveitis, retinopathy, and retinal vasculitis) (177,(234)(235)(236), neurological symptoms (cerebral infarct, meningoencephalitis, sensorineural hearing loss, acute quadriplegia secondary to an axonal polyneuropathy, and motor and sensory polyneuritis) (228,(236)(237)(238)(239)(240)(241), pancreatic involvements (242,243), splenic rupture (244), acute renal failure (245), and the presence of hemophagocytic syndrome (246). In addition to the classical risk factors for malignant MSF (advanced age, immunocompromised situations, chronic alcoholism, glucose-6-phosphate dehydrogenase [G6PD] deficiency, prior prescription of an inappropriate antibiotic, and delay of treatment) (209), alcoholism was definitively confirmed as a risk factor (218), and fluoroquinolone treatment was shown to be associated with increased MSF disease severity and longer hospital stays (238).…”

Section: Tick-borne Rickettsiae In Europe Species Identified As Pathomentioning

confidence: 99%

Update on Tick-Borne Rickettsioses around the World: a Geographic Approach

et al. 2013

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SUMMARY Tick-borne rickettsioses are caused by obligate intracellular bacteria belonging to the spotted fever group of the genus Rickettsia . These zoonoses are among the oldest known vector-borne diseases. However, in the past 25 years, the scope and importance of the recognized tick-associated rickettsial pathogens have increased dramatically, making this complex of diseases an ideal paradigm for the understanding of emerging and reemerging infections. Several species of tick-borne rickettsiae that were considered nonpathogenic for decades are now associated with human infections, and novel Rickettsia species of undetermined pathogenicity continue to be detected in or isolated from ticks around the world. This remarkable expansion of information has been driven largely by the use of molecular techniques that have facilitated the identification of novel and previously recognized rickettsiae in ticks. New approaches, such as swabbing of eschars to obtain material to be tested by PCR, have emerged in recent years and have played a role in describing emerging tick-borne rickettsioses. Here, we present the current knowledge on tick-borne rickettsiae and rickettsioses using a geographic approach toward the epidemiology of these diseases.

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