[.mu.-1,1'-Bis(diphenylphosphino)ferrocene]bis(chlorogold): synthesis, iron-57 and gold-197 Moessbauer spectroscopy, x-ray crystal structure, and antitumor activity

Synthesis of antibacterial and antifungal cobalt(II), copper(II), nickel(II) and zinc(II) complexes with bis‐(1,1′‐disubstituted ferrocenyl)thiocarbohydrazone and bis‐(1,1′‐disubstituted ferrocenyl)carbohydrazone

“…5,6 Enhanced antibacterial activity of penicillin and cephalosporine has also been observed by replacing aromatic groups with the ferrocenyl moiety. 7 Most of the antibiotics used in clinical practice share a common mechanism of action, acting as inhibitors of the bacterial cell wall biosynthesis or affecting protein synthesis on ribosomes but not intervening in more fundamental metabolic processes of the pathogen.…”

Synthesis, characterization, coordination and antibacterial properties of novel asymmetric 1,1′‐disubstituted ferrocene‐derived Schiff‐base ligands and their Co(II), Cu(II) Ni(II) and Zn(II) complexes

“…Different reports [1][2][3][4][5][6] have indicated the use of platinum and gold complexes 7,8 of 1,1'-bis(diphenylphosphino)ferrocene against various tumors. The enhanced antibiotic activity of penicillin and cephalosporine obtained by replacing the aromatic group with the ferrocenyl moiety [9][10][11] has also attracted the attention of many researchers for use of organometallics in biological sciences.…”

Gold chemistry with ferrocene derivatives as Ligands

“…The 197Au and S7Fe Mbssbauer and 31 P NMR spectroscopic data of the products indicate the existence of two different gold (I) coordination geometries in the solid state: linear and trigonal (11). The dinuclear [(dppf)(AuClhl has only marginal activity against the P388 leukaemia mouse model (12) . The crystal structure of one of its known modifications shows a nearly linear P-Au-CI unit and intermolecular goldgold contacts of 3.083(1) A (12), whereas no Au .. ·Au interactions have been found in other modifications of the same compound (14) .…”

“…The reaction of dppf with [AuCI(SR 2 ) lleads to the formation of the chloro complexes [(dppf)(AuClhl (1, X=Cl) , [AuCI(dppf)l and [AuCI(dppfhL depending on the molar ratio used (8,9,12,13). The 197Au and S7Fe Mbssbauer and 31 P NMR spectroscopic data of the products indicate the existence of two different gold (I) coordination geometries in the solid state: linear and trigonal (11).…”

“…The dinuclear [(dppf)(AuClhl has only marginal activity against the P388 leukaemia mouse model (12) . The crystal structure of one of its known modifications shows a nearly linear P-Au-CI unit and intermolecular goldgold contacts of 3.083(1) A (12), whereas no Au .. ·Au interactions have been found in other modifications of the same compound (14) . The reaction of [(dppf)(AuCI) 2l with dppf (1: 1 molar ratio) gives [AuCI(dppf) 1 as an intermediate, which readily polymerizes to give a chain polymer based on trigonal CIAuP 2 units (4) (9,13).…”