Mucociliary Transport and Histologic Characteristics of the Mucosa of Deviated Nasal Septum

Jang, Yong Ju; Myong, Na Hye; Park, Keun Hwan; Koo, Tae Woo; Kim, Han-Gyun

doi:10.1001/archotol.128.4.421

Cited by 68 publications

(62 citation statements)

References 18 publications

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“…In many studies, it has been shown that NSD impaired the nasal MCC mechanism due to ciliary loss, increased inflammation and decreased density in glandular acini [4]. Polat et al [5] demonstrated that nasal mucociliary transport rates (NMTRs) of patients with a deviated septum were significantly lower than the NMTRs of the healthy controls on both the convex and concave sides.…”

Section: Introductionmentioning

confidence: 99%

The Evaluation of Nasal Mucociliary Activity After Septoplasty and External Septorhinoplasty

Sakallıoğlu

Düzer

Kapusuz

et al. 2012

Indian J Otolaryngol Head Neck Surg

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The aim of this study was to evaluate the nasal mucociliary activity after septoplasty (SP) and external septorhinoplasty (eSRP). Twenty patients who had SP operation (group 1) and 15 patients who had eSRP operation (group 2) were enrolled in the study. On each case, mucociliary clearance (MCC) measurement was performed by saccharine test before surgery, and on the first and third months of postoperative period. Saccharine clearance time (SCT) of 28 healthy volunteers were measured to establish control values. The mean SCT in control group was 8.79 ± 2.63 min, in group 1 patients before surgery was 14.03 ± 1.68 min, in group 2 patients before surgery was 14.34 ± 1.70 min. The preoperative SCT values of the group 1 and group 2 were significantly higher than healthy controls (p \ 0.05). While there were statistically significant differences between preoperative and postoperative third month SCT values of group 1 patients, and postoperative first month and postoperative third month SCT values of group 1 patients (p \ 0.05), there was no statistically significant difference between preoperative and postoperative first and third months SCT values of group 2 patients. Nasal septal deviation impairs the nasal mucociliary activity. Septoplasty operation positively affects the MCC mechanism. On the other hand, we observed no significant effect of eSRP operation on mucociliary activity on the first and third months of postoperative period as compared with preoperative.

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Section: Introductionmentioning

confidence: 99%

The Evaluation of Nasal Mucociliary Activity After Septoplasty and External Septorhinoplasty

Sakallıoğlu

Düzer

Kapusuz

et al. 2012

Indian J Otolaryngol Head Neck Surg

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“…In a similar study by Jang et al [8] higher number of infiltrating inflammatory cells were seen in the concave side septal mucosa as compared to the convex side of septal mucosa and the difference was statistically significant. However, they obtained specimen 2 cm posterior to nostril and 1.5 cm inferior to nasal dorsum; in the present study specimen was taken from the most convex part of septum and its opposite side.…”

Section: Discussionmentioning

confidence: 60%

“…Other changes which are seen due to altered air flow dynamics are disturbed mucociliary dysfunction, lymphocytic infiltration and squamous metaplasia. Although these changes are seen on both sides of nasal mucosa, but are more severe on concave side [5][6][7][8][9]. All these changes can be avoided by surgically correcting DNS.…”

Section: Introductionmentioning

confidence: 99%

Influence of Deviated Nasal Septum on Nasal Epithelium: An Analysis

Kumar

Belaldavar

Bannur

2017

Head and Neck Pathol

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“…Septoplasti, nazal septum deviasyonun tek tedavisidir ve geçmiş yıllarda yapılan çalışmalarda belirtildiği gibi septoplasti sonrası mukosiliyer aktivitede artış saptanmaktadır (10). İntranazal tamponlar sıklıkla epistaksisi kontrol altına almak, septoplasti ve septorinoplasti sonrası kullanılır.…”

Section: Discussionunclassified

Comparison of the Postoperative Mucociliary Clearance Time Between Patients who Underwent Septoplasty with and Without Nasal Packing

Çukurova¹,

Gümüşsoy²,

Mengi³

et al. 2013

Turk Arch Otolaryngol

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Objective:To compare the postoperative mucociliary clearance time in septoplasty with and without nasal packing. Methods:Forty-six patients with nasal septal deviation (20 women, 26 men) were assessed in this study. The patients underwent septoplasty under local anaesthesia. Patients were divided in two groups. Merocell® nasal packing was performed in both of the nasal passages for septum stabilization in the first group (28 patients). On the second postoperative day nasal packing was removed and salin irrigation solution was started. Transseptal suturing was performed for nasal stabilization in the second group and at the sixth postoperative hour saline irrigation solution was started. Saccarine clearance test was performed preoperatively and postoperatively at the 7 th day, and 3 th month and the results were compared.Results: In the treatment of 46 patients with a mean age of 20-53, in the first group; preoperative mucociliary clearance time on the deviated side was 12.2 minutes and on the opposite side was 13.1 minutes. In the second group, preoperative mucociliary clearance time on the deviated side was 11.9 minutes, and on the opposite side 12.8 minutes. In the first group, the postoperative 1 th week mucociliary clearance time on the deviated side was 12.5 minutes and on the opposite side was 13.2 minutes and in the second group on the deviated side was 10.1 minutes, and on the opposite side was 10.8 minutes. In the first group, at the postoperative 3 th month mucociliary clearance time on the deviated side was 11.6 minutes and on the opposite side was 11.4 minutes while in the second group on the deviated side was 6.7 minutes, and on the opposite side was 7.8 minutes. Conclusion:The postoperative mucociliary clearance time in patients treated for septal deviation were evaluated. We have determined that the mucociliary clearance time was longer in the patients that underwent septoplasty with nasal packing.Key Words: Mucociliary clearance, septoplasty, nasal septal deviation Abstract Amaç: Tamponlu ve tamponsuz septoplasti uygulanan hastalarda postoperatif mukosiliyer klirens zamanını karşılaştırmak.Yöntemler: Bu çalışmaya nazal deviasyonu olan 20'si kadın, 26'sı erkek 46 hasta alındı. Hastalara lokal anestezi altında septoplasti ameliyatı uygulandı. Hastalar 2 gruba ayrıldı. Birinci gruba (28 hasta), septum stabilizasyonu için her iki nazal pasaja Merocell® tampon yerleştirildi. Postoperatif 2. gün tamponlar çıkarıldı ve salin solusyonu ile irrigasyon başlandı. İkinci gruba (18 hasta) septum stabilizasyonu için transseptal sütürasyon uygulandı ve postoperatif 6.saatte salin solusyonu ile irrigasyon başlandı. Tüm hastalara preoperatif, postoperatif 1. hafta ve 3. ayda sakarin klirens testi uygulandı ve sonuçlar karşılaştırıldı. Bulgular:Yaş dağılımı 20 ile 53 arasında değişen 46 hastaya ait preoperatif nazal mukosiliyer klirens zamanı; birinci grupta deviye tarafta 12,2 dk, deviye olmayan tarafta ise 13,1 dk idi. İkinci grupta deviye tarafta 11,9 dk, deviye olmayan tarafta ise 12,8 dk idi. Postoperatif 1. ...

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Mucociliary Transport and Histologic Characteristics of the Mucosa of Deviated Nasal Septum

Abstract: Concave-side septal mucosae have impaired mucociliary transport, presumably due to ciliary loss, increased inflammation, and decreased density of the glandular acini.

Cited by 68 publications

References 18 publications

The Evaluation of Nasal Mucociliary Activity After Septoplasty and External Septorhinoplasty

The Evaluation of Nasal Mucociliary Activity After Septoplasty and External Septorhinoplasty

Influence of Deviated Nasal Septum on Nasal Epithelium: An Analysis

Comparison of the Postoperative Mucociliary Clearance Time Between Patients who Underwent Septoplasty with and Without Nasal Packing

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