The role of the desiccant used in the dehumidifier is to remove water vapor from the conditioned air due to vapor pressure difference between the hot desiccant and the supply conditioned air. The desiccant can be categorized mainly into the two categories as solid adsorption and liquid absorbent desiccant materials. Several other types of solid materials are available in nature that can hold water vapor to the great extent to its weight, e.g., silica, polymers, zeolites, alumina and mixtures. Other commonly used liquid desiccant materials are calcium chloride, lithium chloride, lithium bromide, triethylene glycol and an equal mixture between calcium chloride and lithium chloride. These liquid desiccants have many thermo-physical properties, but their requirements cannot be fully described by any single desiccant. These requirements include low vapor pressure, low crystallization point, high density, low viscosity, low reactivation temperature, and economy [1]. The moist air is dehumidified by being brought into contact with strong liquid or solid desiccant, after this to provide sensible cooling to dehumidification process, traditional vapor compression, and vapor absorption, direct or indirect evaporative cooler units used. When the solution is weakened by absorption of moisture, it provided for the regeneration process that can loses its moisture content due to external thermal source. This called as reactivating the saturated desiccant material [2]. Thermal energy, at a temperature as low as 46-72°C required for reactivating of the liquid desiccant can efficiently obtained using a particular type of air or water solar collector or other primary heat renewable source [3]. The typical cycle of the desiccant is made up by three processes as shown in Figure 1and Figure 2 depicts the fundamental deviation among traditionally used air conditioner and novel desiccant assisted dehumidification and cooling process [4]. The traditionally used vapor-compression cycle is now the foundation of the world air conditioning industry and will remain so for many years in conjunction with other hybrid cooling systems. The following problems are being addressed through a number of approaches including: (1) More efficient designs for household and commercial air conditioners, (2) More efficient buildings that require minimum or zero cooling, (3) The conversion Abstract: Liquid-desiccant assisted dehumidification and cooling system has been proved to be an effective method to extract the moisture of air with relatively less energy consumption, especially compared with conventional vapor compression system. To date, the conventional dehumidification mode with desiccant solution has been improved or replaced by newly emerged energy-saving systems with better performance. This paper gives a detailed account of the general features of the various components used in desiccant dehumidification and cooling techniques; meanwhile, the effect of various operating parameters on system performance also highlighted. Moreover, a summary of the ex...