Multi-analyte sensing strategies towards wearable and intelligent devices

Huang, Yu; Luo, Cihui; Xia, Fan; Song, Yanlin; Jiang, Lei; Li, Fengyu

doi:10.1039/d2sc03750e

Cited by 21 publications

(21 citation statements)

References 134 publications

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“…The multilayer perceptron neural network of deep learning (DL) algorithms provides the ascendant advantages for a series of complex nonlinear operations and achieves the high-precision identification of different samples. , We collected 150 pressure–capacitance response data points for 15 analytes (1.0 mol/L) as the data set. The obtained 150 pressure–capacitance response data were randomly divided into a train data set (40%), test data set (30%), and validation data set (30%).…”

Section: Resultsmentioning

confidence: 99%

“…The massive complexity and multivariate analysis are the critical challenges of biological system detection and environmental monitoring. 44 Due to the advantages of the distinguished responses of the gel iontronic sensor, we endeavored the adoptability with more chemical substances. Fifteen chemical cosolvents, including 5 cations, 5 anions, and 5 organic cosolvents, were selected for a comprehensive investigation.…”

Section: Resultsmentioning

confidence: 99%

“…The massive complexity and multivariate analysis are the critical challenges of biological system detection and environmental monitoring . Due to the advantages of the distinguished responses of the gel iontronic sensor, we endeavored the adoptability with more chemical substances.…”

Section: Resultsmentioning

confidence: 99%

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Touchable Gustation via a Hoffmeister Gel Iontronic Sensor

Tang

et al. 2023

ACS Nano

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A particular sense, touchable gustation, was achieved. We proposed a chemical–mechanical interface strategy with an iontronic sensor device. A conductive hydrogel, amino trimethylene phosphonic acid (ATMP) assisted poly(vinyl alcohol) (PVA), was employed as the dielectric layer of the gel iontronic sensor. The Hofmeister effect of the ATMP-PVA hydrogel was well investigated to establish the quantitative description of the gel elasticity modulus to chemical cosolvents. The mechanical properties of hydrogels can be transduced extensively and reversibly by regulating the aggregation state of polymer chains with hydrated ions or cosolvents. Scanning electron microscopy (SEM) images of ATMP-PVA hydrogel microstructures stained with different soaked cosolvents present different networks. The information on different chemical components will be stored in the ATMP-PVA gels. The flexible gel iontronic sensor with a hierarchical pyramid structure performed high linear sensitivity of 3224.2 kPa–1 and wide pressure response in the range of 0–100 kPa. The finite element analysis proved the pressure distribution at the gel interface of the gel iontronic sensor and the capacitation–stress response relation. Various cations, anions, amino acids, and saccharides can be discriminated, classified, and quantified with the gel iontronic sensor. The Hofmeister effect regulated chemical–mechanical interface performs the response and conversion of biological/chemical signals into electrical output in real time. The particular function to tactile with gustation percept will contribute promising applications in the human–machine interaction, humanoid robot, clinic treatment, or athletic training optimization.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Touchable Gustation via a Hoffmeister Gel Iontronic Sensor

Tang

et al. 2023

ACS Nano

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“…The blood glucose test has inspired the recognition of carbohydrate as cancer biomarkers for the low cost evaluation of cancer recurrence . The photonic biosensors may promote the handling of complex biological samples. , Field-effect transistors feature the specific and sensitive detection of cancer biomarkers . Overall, graphene biosensors may grow up as an important complementary tool, which coexists with commercial diagnosis strategies including tests by antibody blood, polymerase chain reaction, and immunosorbent assay.…”

Section: Electronic Tongue For Tastementioning

confidence: 99%

Applications of Graphene in Five Senses, Nervous System, and Artificial Muscles

et al. 2023

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Graphene remains of great interest in biomedical applications because of biocompatibility. Diseases relating to human senses interfere with life satisfaction and happiness. Therefore, the restoration by artificial organs or sensory devices may bring a bright future by the recovery of senses in patients. In this review, we update the most recent progress in graphene based sensors for mimicking human senses such as artificial retina for image sensors, artificial eardrums, gas sensors, chemical sensors, and tactile sensors. The brain-like processors are discussed based on conventional transistors as well as memristor related neuromorphic computing. The brain−machine interface is introduced for providing a single pathway. Besides, the artificial muscles based on graphene are summarized in the means of actuators in order to react to the physical world. Future opportunities remain for elevating the performances of human-like sensors and their clinical applications.

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“…A key challenge for designing reaction‐based probe is to find chemical reaction for recognition of particular analyte, biocompatibility, fast kinetics of chemical reaction in water and biorthogonality to avoid interference from endogenous process [9–11] . Now‐a‐days, intelligent sensors are those sensors which can perform multiple analytes sensing at a time at different wavelengths to give multiple readouts [12–13] . Indeed, dual chemosensors which can sense two or more analytes simultaneously or sequentially is an alternative approach but this approach has certain limitations [14–15] .…”

Section: Introductionmentioning

confidence: 99%

Intelligent Colorimetric Sensor for Discriminative Detection of Pd²⁺/Pd⁰ and PPh₃ at Different Wavelength Readouts

et al. 2023

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In this report, we presented our results on a recognition of multiple analytes using trisubstituted PDI-based chemosensor DNP in 50 % HEPES buffered-CH 3 CN solution. Upon addition of Pd 2 + or Pd 0 , DNP showed near IR ratiometric changes (A 759nm / A 560nm ) with detection limit of 283 nM and 190 nM, respectively. These spectroscopic changes are associated with color change from violet to light yellow (de-propargylation). The depropargylation reaction of DNP is faster in the presence of Pd 2 + than Pd 0 . Upon addition of PPh 3 , DNP resulted in appearance of new bands at 615 and 698 nm with decrease of absorbance intensity at 560 nm with detection limit of 349 nM. Two isosbestic points at 504 nm and 600 nm was observed. This change is associated with color changes from violet to blue. DNP coated TLC-strips can be used for the detection of 4 × 10 À 4 M Pd 0 and PPh 3 . We have demonstrated the practical application of DNP (i) for the detection of Pd 0 in live A549 cells and (ii) for detection of Pd 2 + /Pd 0 in simulated urine (10 %) samples with recovery of (> 98 � 5 %).

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Multi-analyte sensing strategies towards wearable and intelligent devices

Abstract: Continuous efforts on functional nanomaterials and flexible/stretchable devices, have promoted the laboratorial, cumbersome detection processes toward the wearable and portable intelligent sensing approaches. Responding to the challenge of multi-analytes, mixture,...

Cited by 21 publications

References 134 publications

Touchable Gustation via a Hoffmeister Gel Iontronic Sensor

Touchable Gustation via a Hoffmeister Gel Iontronic Sensor

Applications of Graphene in Five Senses, Nervous System, and Artificial Muscles

Intelligent Colorimetric Sensor for Discriminative Detection of Pd²⁺/Pd⁰ and PPh₃ at Different Wavelength Readouts

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Multi-analyte sensing strategies towards wearable and intelligent devices

Abstract: Continuous efforts on functional nanomaterials and flexible/stretchable devices, have promoted the laboratorial, cumbersome detection processes toward the wearable and portable intelligent sensing approaches. Responding to the challenge of multi-analytes, mixture,...

Cited by 21 publications

References 134 publications

Touchable Gustation via a Hoffmeister Gel Iontronic Sensor

Touchable Gustation via a Hoffmeister Gel Iontronic Sensor

Applications of Graphene in Five Senses, Nervous System, and Artificial Muscles

Intelligent Colorimetric Sensor for Discriminative Detection of Pd2+/Pd0 and PPh3 at Different Wavelength Readouts

Contact Info

Product

Resources

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Intelligent Colorimetric Sensor for Discriminative Detection of Pd²⁺/Pd⁰ and PPh₃ at Different Wavelength Readouts