This study investigates how window design features, such as size, placement, and orientation, might impact occupants’ behavior related to natural ventilation in residential houses and how residents manage natural ventilation to affect indoor air quality (IAQ), comfort, and energy efficiency. By analyzing responses from a questionnaire distributed among 200 occupants, this article reveals that stuffy air, perceived outdoor pollutants, odors, and relative humidity, along with factors like inadequate ventilation, temperature fluctuations, and energy consumption concerns, emerge as primary issues affecting occupants’ comfort and well-being. This study proposes design recommendations for enhancing IAQ, including optimal window placement for cross-ventilation, window-to-wall ratio (WWR) considerations, and the integration of smart window technologies. This research recognizes that window design is not just a technical matter but involves understanding social and behavioral factors as well. By analyzing occupant responses, it aims to provide insights into the socio-technical parameters that should be considered in window design. The findings offer valuable strategies for architects, designers, and homeowners to optimize natural ventilation and underscore the importance of an occupant-centered approach in sustainable building design.