Multifunctional Bioactive Glasses and Glass-Ceramics: Beyond ‘Traditional’ Bioactivity

Baino, Francesco; Ferraris, Sara; Miola, Marta; Verné, Enrica; Evans, Iain; Bretcanu, Oana

doi:10.1016/b978-0-08-102196-5.00002-1

Cited by 5 publications

(5 citation statements)

References 147 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After 1 day of hPMSCs seeding, the adhered cells spread over the surface, followed by the formation of filopodia and lamellipodia, which exhibit strong anchorage toward the samples. This shows the higher bioactivity potential of the coated samples with BG ions dissolution, supporting the chances of osteointegration properties, which could be correlated with the osteogenic differentiation of hPMSCs. , …”

Section: Resultssupporting

confidence: 54%

Electrophoretic Deposition of 58S Bioactive Glass- Polymer Composite Coatings on 316L Stainless Steel: An Optimization for Corrosion, Bioactivity, and Cytocompatibility

Hadem,

Mitra,

Ojha

et al. 2024

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

This study presents a facile fabrication of 58S bioactive glass (BG)-polymer composite coatings on a 316L stainless steel (SS) substrate using the electrophoretic deposition technique. The suspension characteristics and deposition kinetics of BG, along with three different polymers, namely ethylcellulose (EC), poly(acrylic acid) (PAA), and polyvinylpyrrolidone (PVP), have been utilized to fabricate the coatings. Among all coatings, 58S BG and EC polymers are selected as the final composite coating (EC6) owing to their homogeneity and good adhesion. EC6 coating exhibits a thickness of ∼18 μm and an average roughness of ∼2.5 μm. Herein, EC6 demonstrates better hydroxyapatite formation compared to PAA and PVP coatings in simulated body fluid-based mineralization studies for a period of 28 days. Corrosion studies of EC6 in phosphate-buffered saline further confirm the higher corrosion resistance properties after 14 days. In vitro cytocompatibility studies using human placental mesenchymal stem cells demonstrate an increase in cellular viability, attachment, and higher proliferation compared to the bare SS substrate. EC6 coatings promote osteogenic differentiation, which is confirmed via the upregulation of the OPN and OCN genes. Moreover, the EC6 sample exhibits improved antibacterial properties against Escherichia coli and Staphylococcus aureus compared to the uncoated ones. The findings of this work emphasize the potential of electrophoretically fabricated BG−EC composite coatings on SS substrates for orthopedic applications.

show abstract

Section: Resultssupporting

confidence: 54%

Electrophoretic Deposition of 58S Bioactive Glass- Polymer Composite Coatings on 316L Stainless Steel: An Optimization for Corrosion, Bioactivity, and Cytocompatibility

Hadem,

Mitra,

Ojha

et al. 2024

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

show abstract

“…This is the main drawback of the bioglass formulations currently available on the market. Consequently, many surgeons tend to favor phosphate-based coatings due to their more favorable characteristics in this regard [ 99 , 100 ].…”

Section: Discussionmentioning

confidence: 99%

Advances and challenges in regenerative dentistry: A systematic review of calcium phosphate and silicate-based materials on human dental pulp stem cells

Christie,

Musri,

Djustiana

et al. 2023

Materials Today Bio

View full text Add to dashboard Cite

“…The efficiency of BGs in bone regeneration is also related to the prevention of bacterial adhesion and proliferation that can occur on the implant surface. While BGs are considered good candidates for preventing or reducing this problem, the mechanisms underlying their antibacterial activity are still under study. Among the reported modes of action are the disruption of prokaryotic cell membranes by glass debris , and changes in environmental pH and osmotic pressure .…”

Section: Properties Of Bioactive Glassesmentioning

confidence: 99%

Cerium Containing Bioactive Glasses: A Review

Zambon

Malavasi

Pallini

et al. 2021

ACS Biomater. Sci. Eng.

View full text Add to dashboard Cite

Bioactive glasses (BGs) for biomedical applications are doped with therapeutic inorganic ions (TIIs) in order to improve their performance and reduce the side effects related to the surgical implant. Recent literature in the field shows a rekindled interest toward rare earth elements, in particular cerium, and their catalytic properties. Cerium-doped bioactive glasses (Ce-BGs) differ in compositions, synthetic methods, features, and in vitro assessment. This review provides an overview on the recent development of Ce-BGs for biomedical applications and on the evaluation of their bioactivity, cytocompatibility, antibacterial, antioxidant, and osteogenic and angiogenic properties as a function of their composition and physicochemical parameters.

show abstract

Multifunctional Bioactive Glasses and Glass-Ceramics: Beyond ‘Traditional’ Bioactivity

Cited by 5 publications

References 147 publications

Electrophoretic Deposition of 58S Bioactive Glass- Polymer Composite Coatings on 316L Stainless Steel: An Optimization for Corrosion, Bioactivity, and Cytocompatibility

Electrophoretic Deposition of 58S Bioactive Glass- Polymer Composite Coatings on 316L Stainless Steel: An Optimization for Corrosion, Bioactivity, and Cytocompatibility

Advances and challenges in regenerative dentistry: A systematic review of calcium phosphate and silicate-based materials on human dental pulp stem cells

Cerium Containing Bioactive Glasses: A Review

Contact Info

Product

Resources

About