Multifunctional Eco-Friendly Synthesis of ZnO Nanoparticles in Biomedical Applications

Al-Mohaimeed, Amal M.; Al-onazi, Wedad A.; El‐Tohamy, Maha F.

doi:10.3390/molecules27020579

Cited by 34 publications

(17 citation statements)

References 87 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This efficacy is linked to the morphology and structure of the nanomaterials used and bacterial colonies’ features. Our results are comparable with those obtained by other nanomaterials having similar sizes, e.g., Ag NPs/ZnO nanohybrid [ 81 ] or ZnO nanoflowers [ 82 ] or ZnO NPs [ 25 ], Ag doped ZnO NPs and Au doped ZnO NPs [ 83 ].…”

Section: Resultssupporting

confidence: 89%

Synthesis of ZnO/Au Nanocomposite for Antibacterial Applications

Dediu

Bușilă²,

Ţucureanu³

et al. 2022

Nanomaterials

View full text Add to dashboard Cite

Annually, antimicrobial-resistant infections-related mortality worldwide accelerates due to the increased use of antibiotics during the coronavirus pandemic and the antimicrobial resistance, which grows exponentially, and disproportionately to the current rate of development of new antibiotics. Nanoparticles can be an alternative to the current therapeutic approach against multi-drug resistance microorganisms caused infections. The motivation behind this work was to find a superior antibacterial nanomaterial, which can be efficient, biocompatible, and stable in time. This study evaluated the antibacterial activity of ZnO-based nanomaterials with different morphologies, synthesized through the solvothermal method and further modified with Au nanoparticles through wet chemical reduction. The structure, crystallinity, and morphology of ZnO and ZnO/Au nanomaterials have been investigated with XRD, SEM, TEM, DLS, and FTIR spectroscopy. The antibacterial effect of unmodified ZnO and ZnO/Au nanomaterials against Escherichia coli and Staphylococcus aureus was investigated through disc diffusion and tetrazolium/formazan (TTC) assays. The results showed that the proposed nanomaterials exhibited significant antibacterial effects on the Gram-positive and Gram-negative bacteria. Furthermore, ZnO nanorods with diameters smaller than 50 nm showed better antibacterial activity than ZnO nanorods with larger dimensions. The antibacterial efficiency against Escherichia coli and Staphylococcus aureus improved considerably by adding 0.2% (w/w) Au to ZnO nanorods. The results indicated the new materials’ potential for antibacterial applications.

show abstract

Section: Resultssupporting

confidence: 89%

Synthesis of ZnO/Au Nanocomposite for Antibacterial Applications

Dediu

Bușilă²,

Ţucureanu³

et al. 2022

Nanomaterials

View full text Add to dashboard Cite

show abstract

“…J.F. Macbr Hexagonal 40–50 63 Phoenix dactylifera L Spherical 22 64 Avena Sativa L Hexagonal 100 65 Limonium pruinosum (L.) Chaz Hexagonal/cubic ~ 41 Present study …”

Section: Resultsmentioning

confidence: 68%

Green synthesis of zinc oxide nanoparticles using Sea Lavender (Limonium pruinosum L. Chaz.) extract: characterization, evaluation of anti-skin cancer, antimicrobial and antioxidant potentials

Naiel

Fawzy

Halmy

et al. 2022

Sci Rep

102

View full text Add to dashboard Cite

In the present study, a green, sustainable, simple and low-cost method was adopted for the synthesis of ZnO NPs, for the first time, using the aqueous extract of sea lavender, Limonium pruinosum (L.) Chaz., as a reducing, capping, and stabilizing agent. The obtained ZnO NPs were characterized using ultraviolet–visible spectroscopy (UV–VIS), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDX), transmission electron microscopy (TEM), X-ray diffraction (XRD) and thermogravimetric analysis (TGA). The UV–Vis spectra of the green synthesized ZnO NPs showed a strong absorption peak at about 370 nm. Both electron microscopy and XRD confirmed the hexagonal/cubic crystalline structure of ZnO NPs with an average size ~ 41 nm. It is worth noting that the cytotoxic effect of the ZnO NPs on the investigated cancer cells is dose-dependent. The IC50 of skin cancer was obtained at 409.7 µg/ml ZnO NPs. Also, the phyto-synthesized nanoparticles exhibited potent antibacterial and antifungal activity particularly against Gram negative bacteria Escherichia coli (ATCC 8739) and the pathogenic fungus Candida albicans (ATCC 10221). Furthermore, they showed considerable antioxidant potential. Thus, making them a promising biocompatible candidate for pharmacological and therapeutic applications.

show abstract

“…Among the metal nanoparticles, ZnO and TiO 2 possess great potential to fight against diverse type of microorganisms. Therefore, nanoparticles of metal oxides (ZnO or TiO 2 ) capable of generating highly reactive radicals can be incorporated into polymer matrices in order to give them biological, electrical, optical, and/or photocatalytic activity, as well as to improve their thermal and physicomechanical properties [ 100 , 101 ]. TiO 2 is known in the literature to exhibit antibacterial properties against both bacteria and fungi.…”

Section: Electrospun Fibrous Materials With Antifungal Activity Again...mentioning

confidence: 99%

Electrospun Polymer Materials with Fungicidal Activity: A Review

et al. 2022

View full text Add to dashboard Cite

In recent years, there has been special interest in innovative technologies such as polymer melt or solution electrospinning, electrospraying, centrifugal electrospinning, coaxial electrospinning, and others. Applying these electrokinetic methods, micro- or nanofibrous materials with high specific surface area, high porosity, and various designs for diverse applications could be created. By using these techniques it is possible to obtain fibrous materials from both synthetic and natural biocompatible and biodegradable polymers, harmless to the environment. Incorporation of low-molecular substances with biological activity (e.g., antimicrobial, antifungal) is easily feasible. Moreover, biocontrol agents, able to suppress the development and growth of plant pathogens, have been embedded in the fibrous materials as well. The application of such nanotechnologies for the creation of plant protection products is an extremely promising new direction. This review emphasizes the recent progress in the development of electrospun fungicidal dressings and their potential to be applied in modern agriculture.

show abstract

Multifunctional Eco-Friendly Synthesis of ZnO Nanoparticles in Biomedical Applications

Cited by 34 publications

References 87 publications

Synthesis of ZnO/Au Nanocomposite for Antibacterial Applications

Synthesis of ZnO/Au Nanocomposite for Antibacterial Applications

Green synthesis of zinc oxide nanoparticles using Sea Lavender (Limonium pruinosum L. Chaz.) extract: characterization, evaluation of anti-skin cancer, antimicrobial and antioxidant potentials

Electrospun Polymer Materials with Fungicidal Activity: A Review

Contact Info

Product

Resources

About