The brain is an important organ that directs all the actions of the body and the intervention that it has in human behavior, is fundamental for the analysis of the subject since by means of its study it can be analyzed its structure, functioning, coordination, and control. Exercises in different actions, where they link the knowledge of What is the brain?. What is learning?. And What is neuroscience? to recognize the impact they exert on the daily actions of the human being. The present work uses the bibliographic reference where the information will have sustained, which aims to define the importance of the Brain and its relationship in learning activities, through experience and knowledge. Finally, the conclusions of the work ha exposed, where technological and scientific advances have detailed with respect to the importance of the brain in the learning and teaching processes, from different sciences, understanding the importance and development of the knowledge.