Multiple increase in productivity of the yeast at reducing the fraction of D2O in water

Першин, С. М.; Ismailov, E. Sh.; Dibirova, M. M.; Ахмедов, М. А.; Tagirova, F. V.; Shashkov, D. I.; Abdulmagomedova, Z. N.

doi:10.1134/s1607672917050039

Cited by 8 publications

(3 citation statements)

References 8 publications

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“…Winey has documented fractal-like branching of well-defined vortices in mixtures of whole cow's milk and vinegar after experimental milk samples were exposed to torsion fields [109]. https://www.researchgate.net/publication/353183316_Branching_Vortices_of_Raw_Milk_and_Vinegar_with_red_food _coloring_for_contrast Under the recently introduced NGTC/ascorbolysis/UNMR theoretical framework [11,15], gene expression, editing, recycling, and error correction, might be regulated and mediated by L-ascorbic acid, the L-ascorbic acid free radical, and ortho and para nuclear spin states of water (spin water) [110][111][112] , within a moderately acidic, mildly oxidative, relatively hydrophobic microenvironment [11,15]. L-ascorbic acid levels are known to be high in lymphoid tissue [113][114][115][116][117][118][119][120].…”

Section: Ensemble (Composite) Molecular Chirality May Prove To Be An ...mentioning

confidence: 99%

Are the mRNA vaccines inducing the Sanarelli-Shwartzman phenomenon?

Davidson¹,

Winey²

2022

GSC Adv. Res. Rev.

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Adverse events of myocarditis, pericarditis, and thrombosis, temporally associated with mRNA vaccination(s) and/or mRNA vaccine boosters, have been reported during post-marketing safety surveillance in the U.S. CDC VAERS database and 2021 CDC guidance to physicians. An interim report unexpectedly revealed inflammatory biomarker elevations in vaccine recipients. During review of considerable published research on the Sanarelli-Shwartzman phenomenon (SSP) and the use of nucleic acids as vaccine adjuvants, a novel, hypothesis is proposed. Even today, after being studied for over a century, the pathophysiology of the SSP is not fully understood. Motivated by a paper from 1950, titled “General Adaptation Syndrome” by Hans Selye, and recent published research by Korean investigators, a novel, non-conventional hypothesis was generated. Gluten and lectin sensitivity are cited as examples of sensitizing events of the SSP, for which we propose ensemble hydrophobic chiroptical catalysis may have therapeutic benefit. Under the ensemble HCC hypothesis, we propose that inflammatory stress and scurvy promote loss of chirality control, anomeric fidelity, phenotypic stability, and immune function, both humoral and cell-mediated, with the dialyzable transfer factor, L-ascorbic acid, and spin water playing central roles. It is proposed that therapeutic synergy of L-ascorbic acid, bioflavonoids, and corticosteroids in countering the SARS-CoV-2 pathogen arises from memory of chirality which originated during their biosynthesis. It is proposed that ensemble HCC is powered by radiant and or zero-point energy (quantum vacuum fluctuations) which may support a paradigm shift to supramolecular biology. The distinction between supramolecular biology and supramolecular xenobiology is highlighted.

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Section: Ensemble (Composite) Molecular Chirality May Prove To Be An ...mentioning

confidence: 99%

Are the mRNA vaccines inducing the Sanarelli-Shwartzman phenomenon?

Davidson¹,

Winey²

2022

GSC Adv. Res. Rev.

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“…Changes in deuterium content can have a profound effect on the physiological processes in the body [1,2]. The creation of modern methods for deuterium-depleted water (DDW) production [3][4][5][6][7] has made possible the targeted regulation of HDO molecule levels in drinking water while tracking the response of various organs and body systems.…”

Section: Introductionmentioning

confidence: 99%

Electrophysiological Activity and Survival Rate of Rats Nervous Tissue Cells Depends on D/H Isotopic Composition of Medium

et al. 2021

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The deuterium content modification in an organism has a neuroprotective effect during the hypoxia model, affecting anxiety, memory and stress resistance. The aim of this work was to elucidate the possible mechanisms of the medium D/H composition modification on nerve cells. We studied the effect of an incubation medium with a 50 ppm deuterium content compared to a medium with 150 ppm on: (1) the activity of Wistar rats’ hippocampus CA1 field neurons, (2) the level of cultured cerebellar neuron death during glucose deprivation and temperature stress, (3) mitochondrial membrane potential (MMP) and the generation of reactive oxygen species in cultures of cerebellar neurons. The results of the analysis showed that the incubation of hippocampal sections in a medium with a 50 ppm deuterium reduced the amplitude of the pop-spike. The restoration of neuron activity was observed when sections were returned to the incubation medium with a 150 ppm deuterium content. An environment with a 50 ppm deuterium did not significantly affect the level of reactive oxygen species in neuron cultures, while MMP decreased by 16–20%. In experiments with glucose deprivation and temperature stress, the medium with 50 ppm increased the death of neurons. Thus, a short exposure of nerve cells in the medium with 50 ppm deuterium acts as an additional stressful factor, which is possibly associated with the violation of the cell energy balance. The decrease in the mitochondrial membrane potential, which is known to be associated with ATP synthesis, indicates that this effect may be associated with the cell energy imbalance. The decrease in the activity of the CA1 field hippocampal neurons may reflect reversible adaptive changes in the operation of fast-reacting ion channels.

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“…At the cellular level the studies are conducted to find out the effect of DDW on oncoculture; Cong F.-S. et al showed that DDW induces apoptosis in human lung carcinoma cell line A549 in vitro, and also reduces lung tumor size in mice in vivo by 30% [16]; and Wang H. et al showed the efficiency of DDW to inhibit the proliferation of nasopharyngeal carcinoma cells [17]. In addition, studies are conducted of DDW influence for dynamics of growth and activity of various microorganisms, for example it is shown that yeast cells, taken as tested objects, double increase production of CO 2 yield in a nutrient mixture prepared in light water with depleted content of deuterium [18].…”

Section: Introductionmentioning

confidence: 99%

Change of 2H/1H Ratio and Adaptive Potential in Living Systems under Formation of Isotope Gradient

Джимак

Fedulova

Моисеев

et al. 2019

J. Pharm. Nutr. Sci.

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This article presents data on ability of drinking water with depleted concentrations of deuterium (deuterim depleted water – DDW, ?2H = -762 ‰) to influence on the adaptive capacities and functional activity of rats organism during long period of DDW consumption. The obtained data confirms the favorable effect of reduced ?2H on hepatocytes of medium and shows significant (by 10%) increase of body weight among rats which consumed DDW for 3 weeks after birth. It is also shown that when rats consumed DDW, the non-uniform distribution of deuterium in the blood plasma and liver, kidney and heart tissues is observed. At the same time under natural conditions ?2H was significantly lower in blood plasma than in tissues of internal organs (?2H plasma > ?2H of tissues of internal organs), whereas DDW consumption resulted in more significant decrease of ?2H level in blood plasma than in the internal organs, which phenomena was accompanied by change of direction of 2H/1H isotope gradient: ?2H of plasma < ?2H of tissue of internal organs. Stable change in direction of 2H/1H isotope gradient over 3 weeks is expressed by lower rate of weight gain in the first generation of rats. All these facts can be caused by influence of 2H/1H isotope gradient on long-term adaptation mechanisms, but not on short-term adaptation reactions. Decrease of ?2H in blood plasma and tissues of internal organs increases to a greater extent the resistance of an organism to influence of unfavorable environmental factors among future generations of rats consuming DDW for a long time.

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Multiple increase in productivity of the yeast at reducing the fraction of D2O in water

Cited by 8 publications

References 8 publications

Are the mRNA vaccines inducing the Sanarelli-Shwartzman phenomenon?

Are the mRNA vaccines inducing the Sanarelli-Shwartzman phenomenon?

Electrophysiological Activity and Survival Rate of Rats Nervous Tissue Cells Depends on D/H Isotopic Composition of Medium

Change of 2H/1H Ratio and Adaptive Potential in Living Systems under Formation of Isotope Gradient

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