Multiplex measurement of twelve tumor markers using a GMR multi-biomarker immunoassay biosensor

Gao, Yinghui; Huo, Weisong; Zhang, Lei; Lian, Jing; Tao, Wei Qing; Song, Chaoyun; Tang, Jinping; Shi, Stone D.-H.; Gao, Yunhua

doi:10.1016/j.bios.2018.08.060

Cited by 94 publications

(68 citation statements)

References 31 publications

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“…Volume-based and surface-based magnetic biosensors have been applied for the diagnosis of viruses, pathogens, cancer biomarkers, metallic ions, etc. ( Aytur et al, 2006 ; Gao et al, 2019 ; Hash et al, 2019 ; Klein et al, 2019 ; Lin, Lu, Ge, Cai, & Grimes, 2010 ; Rettcher et al, 2015 ; Su et al, 2019 ; Wang, Yang, Lei, Lei, & Zhou, 2014 , 2014b ; Wu et al, 2020 ; Zou et al, 2019 ). Indeed, magnetic biosensors are coupled with antibodies or DNA/RNA probes that can attach to the target cells specifically, and then, the amount of the target cells affects the magnetic signals.…”

Section: Metal-based Nanoparticlesmentioning

confidence: 99%

Role of different types of nanomaterials against diagnosis, prevention and therapy of COVID-19

Ghaemi

Amiri

Bajuri

et al. 2021

Sustainable Cities and Society

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Section: Metal-based Nanoparticlesmentioning

confidence: 99%

Role of different types of nanomaterials against diagnosis, prevention and therapy of COVID-19

Ghaemi

Amiri

Bajuri

et al. 2021

Sustainable Cities and Society

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“…The biosensor possesses a wide DR and excellent precision with an inaccuracy established by a coefficient of variation of less than 10%. [56] A simple wedge-shaped microfluidic device efficiently isolates (capture efficiency (CE) greater than 85%) and identifies CTCs in the whole blood sample from patients with one of several tumors, including liver cancer, breast cancer, lung cancer, and gastric cancer, as reported by Qin et al The device has high CE and can separate CTCs in blood samples from various cancers. [57] When tumor spheroids are trapped in a microfluidic chip, a quantitative hyperspectral imaging (HSI) system with a wide-area ability allows the simultaneous measurement of 60 tumor spheroids in one acquisition and perform multiple point-in-time analyses, as explained by Stgeorgesrobillard et al Besides, the HSI system does not damage the 3D cells during the detection process.…”

Section: Multifunction Devicementioning

confidence: 99%

Advanced Devices for Tumor Diagnosis and Therapy

Wang

Dai

Lan

et al. 2021

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Chinese mythology says that in the time of the Chou Dynasty ten suns were present in the sky, leading to a hard life for people because of the enormous heat. A hero named "Houyi" At present, tumor diagnosis is performed using common procedures, which are slow, costly, and still presenting difficulties in diagnosing tumors at their early stage. Tumor therapeutic methods also mainly rely on large-scale equipment or non-intelligent treatment approaches. Thus, an early and accurate tumor diagnosis and personalized treatment may represent the best treatment option for a successful result, and the efforts in finding them are still in progress and mainly focusing on non-destructive, integrated, and multiple technologies. These objectives can be achieved with the development of advanced devices and smart technology that represent the topic of the current investigations. Therefore, this review summarizes the progress in tumor diagnosis and therapy and briefly explains the advantages and disadvantages of the described microdevices, finally proposing advanced micro smart devices as the future development trend for tumor diagnosis and therapy.was sent from heaven to shoot down nine suns, leaving only the one that is still shining today to allow a normal life for people (Scheme 1). In real life, cancer threatens people's lives like the nine suns in mythology. The history of the struggle between human beings and tumors is represented by the development of science and technology. The diagnosis of diseases in ancient China by the Chinese medicine used the approach of "observing, listening, asking, and pulse feeling". Observing is referred to as the general inspection of the body and tongue inspection. Listening is referred to listening to sounds and smelling odor. Asking is referred to ask the symptoms. Pulse feeling represents the use of fingers to evaluate the radial artery pulsation behind the wrist, and it represents the essence of the diagnosis by traditional Chinese medicine. It is also the most difficult one among the four diagnostic methods because doctor should determine which organs have lesions from the pulsation changes, which is difficult to perceive by ordinary people. Therefore, without any anatomy support, pulse feeling in the diagnosis of incurable diseases has very large limitations. Pulse feeling can be replaced by intuitive diagnostic techniques in modern medicine. Indeed, tumors are diagnosed in various ways thanks to the development of modern science and technology, and the ever-evolving therapy technology is also transformed into an "arrow of Houyi" to shoot the "poisonous sun" that threatens human health.A timely and accurate diagnosis of cancer is crucial for choosing the correct treatment plan for a consequent successful cure. Usually, the methods to diagnose tumors include imaging, endoscopic investigation, and diagnostic pathology. Pathology techniques are important in clinical diagnosis, but they require biopsy and cannot be monitored in real time. Endoscopic technology allows a direct tumor monitori...

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“…[114][115][116] Through surface modification of MNPs, this platform can be widely used for detection of several biological targets as shown in Figure 5A,B. [113,[117][118][119][120][121][122].…”

Section: Gmr-based Bioassaymentioning

confidence: 99%

Magnetic Particles: Their Applications from Sample Preparations to Biosensing Platforms

et al. 2020

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The growing interest in magnetic materials as a universal tool has been shown by an increasing number of scientific publications regarding magnetic materials and its various applications. Substantial progress has been recently made on the synthesis of magnetic iron oxide particles in terms of size, chemical composition, and surface chemistry. In addition, surface layers of polymers, silica, biomolecules, etc., on magnetic particles, can be modified to obtain affinity to target molecules. The developed magnetic iron oxide particles have been significantly utilized for diagnostic applications, such as sample preparations and biosensing platforms, leading to the selectivity and sensitivity against target molecules and the ease of use in the sensing systems. For the process of sample preparations, the magnetic particles do assist in target isolation from biological environments, having non-specific molecules and undesired molecules. Moreover, the magnetic particles can be easily applied for various methods of biosensing devices, such as optical, electrochemical, and magnetic phenomena-based methods, and also any methods combined with microfluidic systems. Here we review the utilization of magnetic materials in the isolation/preconcentration of various molecules and cells, and their use in various techniques for diagnostic biosensors that may greatly contribute to future innovation in point-of-care and high-throughput automation systems.

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Multiplex measurement of twelve tumor markers using a GMR multi-biomarker immunoassay biosensor

Cited by 94 publications

References 31 publications

Role of different types of nanomaterials against diagnosis, prevention and therapy of COVID-19

Role of different types of nanomaterials against diagnosis, prevention and therapy of COVID-19

Advanced Devices for Tumor Diagnosis and Therapy

Magnetic Particles: Their Applications from Sample Preparations to Biosensing Platforms

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