Mus spretus (Rodentia: Muridae)

Palomo, L. Javier; Justo, Enrique R.; Vargas, J. Mario

doi:10.1644/840.1

Cited by 46 publications

(41 citation statements)

References 65 publications

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“…M. spretus separated from M. musculus spp. ~1.5 to 3 million years ago [12]. The species are more strongly reproductively isolated than is predicted by Haldane’s Rule [13, 14], i.e.…”

Section: Resultsmentioning

confidence: 99%

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Adaptive Introgression of Anticoagulant Rodent Poison Resistance by Hybridization between Old World Mice

Song

Endepols

Klemann³

et al. 2011

Current Biology

304

375

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Summary It is known that evolution by selection on new or standing single nucleotide polymorphisms (SNPs) in the vitamin K 2,3-epoxide reductase subcomponent 1 (vkorc1) of house mice (Mus musculus domesticus) can cause resistance to anticoagulant rodenticides such as warfarin [1–3]. Here we report an introgression in European M. m. domesticus spanning as much as ~20.3 megabases (Mb) and including vkorc1, the molecular target of anticoagulants [1–4], that stems from hybridization with the Algerian mouse (M. spretus). We show that in the laboratory the homozygous complete vkorc1 allele of M. spretus confers resistance when introgressed into M. m. domesticus. Consistent with selection on the introgression after the introduction of rodenticides in the 1950s we document historically adaptive population genetics of vkorc1 in M. m. domesticus. Furthermore, we detected adaptive protein evolution of vkorc1 in the M. spretus lineage (Ka/Ks=1.54–1.93) resulting in radical amino-acid substitutions that apparently have anticoagulant tolerance of M. spretus as pleiotropic effect. Thus, positive selection produced an adaptive, divergent and pleiotropic vkorc1 allele in the donor species, M. spretus, which crossed a species barrier where it is expressed as adaptive trait in the recipient species, M. m. domesticus. Resistant house mice originated from selection on new or standing vkorc1 polymorphisms and from selection on vkorc1 polymorphisms acquired by adaptive introgressive hybridization.

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“…M. spretus separated from M. musculus spp. ~1.5 to 3 million years ago [12]. The species are more strongly reproductively isolated than is predicted by Haldane’s Rule [13, 14], i.e.…”

Section: Resultsmentioning

confidence: 99%

“…B) Distribution of vkorc1 genotypes in Western European M. m. domesticus . The hatched area depicts the native range of M. spretus [12]. The house mouse has become a cosmopolitan species and now is occurring across the entire area depicted and beyond [29].…”

Section: Figurementioning

confidence: 99%

Adaptive Introgression of Anticoagulant Rodent Poison Resistance by Hybridization between Old World Mice

Song

Endepols

Klemann³

et al. 2011

Current Biology

304

375

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“…The Algerian mouse in the Iberian Peninsula has been described as mainly nocturnal except in winter, when it is multiphasic (Palomo et al. ). Similarly, the wood mouse has been described as predominantly nocturnal (Wolton ), even though some diurnal activity has also occasionally been registered (Flowerdew ).…”

Section: Discussionmentioning

confidence: 99%

Catch Me If You Can: Diel Activity Patterns of Mammalian Prey and Predators

2013

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The activity patterns exhibited by animals are shaped by evolution, but additionally fine‐tuned by flexible responses to the environment. Predation risk and resource availability are environmental cues which influence the behavioural decisions that make both predators and prey engage in activity bursts, and depending on their local importance, can be strong enough to override the endogenous regulation of an animals’ circadian clock. In Southern Europe, wherever the European rabbit (Oryctolagus cuniculus) is abundant, it is the main prey of most mammalian mesopredators, and rodents are generally the alternative prey. We evaluated the bidirectional relation between the diel activity strategies of these mammalian mesopredators and prey coexisting in south‐western Europe. Results revealed that even though predation risk enforced by mammalian mesocarnivores during night‐time was approximately twice and five times higher than during twilight and daytime, respectively, murids consistently displayed unimodal nocturnal behaviour. Conversely, the European rabbits exhibited a bimodal pattern that peaked around sunrise and sunset. Despite the existence of some overlap between the diel rhythms of mesocarnivores and rabbits, their patterns were not synchronized. We suggest that the environmental stressors in our study areas are not severe enough to override the endogenous regulation of the circadian cycle in murids. European rabbits, however, are able to suppress their biological tendency for nocturnality by selecting a predominantly crepuscular pattern. In spite of the higher energetic input, mesocarnivores do not completely track rabbits’ activity pattern. They rather track rodents’ activity. We propose that these systems have probably evolved towards a situation where some degree of activity during high‐risk periods benefits the overall prey population survival, while the accessibility to sufficient prey prevents predators to completely track them.

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“…This distinct pattern probably reflects both the seasonal patterns of population abundance and the habitat preferences of the studied species. Our study took place in late October, at the beginning of the wet season, when the abundance of M. spretus is at its annual peak following the spring and summer reproductive period (Palomo et al 2009). Conversely, A. sylvaticus and C. russula populations were at their lowest levels since their peak reproductive period occurs after the period covered by our study, during the winter months (Torre et al 2002;Pita et al 2003).…”

Section: Discussionmentioning

confidence: 99%

“…Conversely, A. sylvaticus and C. russula populations were at their lowest levels since their peak reproductive period occurs after the period covered by our study, during the winter months (Torre et al 2002;Pita et al 2003). The higher number of captures of M. spretus may also be a consequence of the main habitat type in the matrix (grassland) surrounding the sampling sites, since M. spretus prefers open fields with tall grass (Palomo et al 2009), while A. sylvaticus often resides in fields with high forest cover (Torre et al 2002). C. russula shows a mixed pattern of habitat use: it often is associated with open landscapes and cultivated fields (Michel et al 2007), but it appears to concentrate in forested patches during the winter season (De Alba et al 2001).…”

Section: Discussionmentioning

confidence: 99%

Living on the verge: are roads a more suitable refuge for small mammals than streams in Mediterranean pastureland?

Sabino-Marques

Mira

2010

Ecological Research

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The retention of natural habitat corridors is a useful and practical conservation tool that can attenuate the effects of habitat loss and fragmentation on wildlife. Linear structures may contribute to the conservation of biodiversity by providing additional habitats for small fauna living in highly modified environments. We assessed the importance of road verges as refuge areas for small mammals, in highly intensified grazed pastures, within a Mediterranean landscape and compared the role of road verges as refuges with that of riparian galleries, which have been described as important shelter locations for small fauna. For this purpose, a small mammal trapping study was undertaken on two road verges and beside two small streams in southern Portugal. We captured 457 individuals of five different species, with Mus spretus the most common species captured, followed by Crocidura russula. Captures were 4.6-fold higher immediately beside both roads and streams than 12 m away in the surrounding matrix. Individuals captured in the matrix presented a smaller body size and lower body condition, suggesting that this suboptimal habitat is occupied mainly by subadults. M. spretus was 46% more abundant by roads than by streams, while C. russula was present in similar numbers in both habitats. M. spretus individuals were larger near streams but exhibited no difference in body condition between habitats. C. russula had a better body condition and slightly higher body lengths at roadsides. Our results show that roadside verges in intensively grazed Mediterranean landscapes act as important refuges and constitute equally vital habitats for small mammals as do riparian vegetation strips in landscapes where other suitable habitats are scarce.

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Mus spretus (Rodentia: Muridae)

Cited by 46 publications

References 65 publications

Adaptive Introgression of Anticoagulant Rodent Poison Resistance by Hybridization between Old World Mice

Adaptive Introgression of Anticoagulant Rodent Poison Resistance by Hybridization between Old World Mice

Catch Me If You Can: Diel Activity Patterns of Mammalian Prey and Predators

Living on the verge: are roads a more suitable refuge for small mammals than streams in Mediterranean pastureland?

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