Mussel-inspired immobilization of zwitterionic silver nanoparticles toward antibacterial cotton gauze for promoting wound healing

Xiang, Jun; Zhu, Ruixin; Lang, Shiying; Yan, Hui; Liu, Gongyan; Peng, Biyu

doi:10.1016/j.cej.2020.128291

Cited by 114 publications

(80 citation statements)

References 51 publications

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“…39,40 Due to the zwitterionic characteristic, it can be assumed that modified chitosan could be used in metal adsorption, 41 for example, in water purification and medical applications. 42 3.4. Preparation of a Film from Modified Chitosan.…”

Section: Resultsmentioning

confidence: 99%

Aqueous Modification of Chitosan with Itaconic Acid to Produce Strong Oxygen Barrier Film

et al. 2021

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In this study, the chemical modification of chitosan using itaconic acid as a natural-based unsaturated dicarboxylic acid was investigated. In an aqueous environment, the amine group of chitosan reacts with itaconic acid to produce a chitosan derivative with pyrrolidone-4-carboxylic acid group. On the basis of the elemental analysis, 15% of the amine groups of chitosan reacted, thus creating modified chitosan with amine and carboxylic acid functionalities. Due to the presence of amine and carboxylic acid groups, the surface charge properties of the chitosan were notably altered after itaconic acid modification. In an aqueous solution, the modified chitosan exhibited zwitterionic properties, being cationic at low pH and turning anionic when the pH was increased over 6.5, whereas the original chitosan remained cationic until pH 9. Furthermore, it was demostrated that the modified chitosan was suitable for the preparation of a self-standing film with similarly high transparency but notably higher mechanical strength and oxygen barrier properties compared to a film made from the original chitosan. In addition, the thermal stability of the modified chitosan film was higher than that of the original chitosan film, and the modified chitosan exhibited flame-retardant properties.

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Section: Resultsmentioning

confidence: 99%

Aqueous Modification of Chitosan with Itaconic Acid to Produce Strong Oxygen Barrier Film

et al. 2021

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“…Some of these strategies that are being presently adopted to treat SSIs associated with biofilm formation are: inhibiting the attachment of the microorganisms to the substratum, using special compounds that interfere with and unsettle the biofilm structure, and disrupting the biofilm at the initial stages [ 22 , 23 ]. For example, to help control the rate of SSIs, new antiadhesive surfaces with altered physical, chemical, and topographical properties that prevent microbial adhesion and thereby biofilm formation have been tested on several medical devices [ 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ].…”

Section: Novel Strategies To Control Biofilm-associated Ssismentioning

confidence: 99%

Biofilms in Surgical Site Infections: Recent Advances and Novel Prevention and Eradication Strategies

2022

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Surgical site infections (SSIs) are common postoperative occurrences due to contamination of the surgical wound or implanted medical devices with community or hospital-acquired microorganisms, as well as other endogenous opportunistic microbes. Despite numerous rules and guidelines applied to prevent these infections, SSI rates are considerably high, constituting a threat to the healthcare system in terms of morbidity, prolonged hospitalization, and death. Approximately 80% of human SSIs, including chronic wound infections, are related to biofilm-forming bacteria. Biofilm-associated SSIs are extremely difficult to treat with conventional antibiotics due to several tolerance mechanisms provided by the multidrug-resistant bacteria, usually arranged as polymicrobial communities. In this review, novel strategies to control, i.e., prevent and eradicate, biofilms in SSIs are presented and discussed, focusing mainly on two attractive approaches: the use of nanotechnology-based composites and natural plant-based products. An overview of new therapeutic agents and strategic approaches to control epidemic multidrug-resistant pathogenic microorganisms, particularly when biofilms are present, is provided alongside other combinatorial approaches as attempts to obtain synergistic effects with conventional antibiotics and restore their efficacy to treat biofilm-mediated SSIs. Some detection and real-time monitoring systems to improve biofilm control strategies and diagnosis of human infections are also discussed.

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“…Compared with other PTAs, AuNPs are easy to prepare, 38 and the light sources of AuNPs used for PTT could be visible light, which are easier to attain. In addition, compared with other methods reported to synthesis antimicrobial cotton gauzes, [11][12][13][14][15][16] the immersing and heating procedure used to synthesis AuNPs modied cotton gauzes is easy to operate. What's more, only a short treatment time of 40 s was needed to fully kill the microbial cells permeated in the cotton gauze, making the therapy extremely efficient.…”

Section: Antimicrobial Ability Of Aunps Modied Cotton Gauzementioning

confidence: 99%

“…[6][7][8][9][10] There are two basic methods to enhance the antimicrobial ability of cotton gauze: one is the chemical method, and the other is the physical method. The chemical method is incorporating antimicrobial agents, such as an antimicrobial drug, 11 metal component, 12,13 antimicrobial peptide, 8 polycation, 14 or ionic liquid 15 to enhance the antimicrobial ability. Xiang et al 12 used mussel-inspired catechol/amino chemistry to immobilize zwitterionic AgNPs on cotton gauze, and the sustained release of Ag + could give the modied cotton gauze excellent bactericidal activity.…”

Section: Introductionmentioning

confidence: 99%

“…The chemical method is incorporating antimicrobial agents, such as an antimicrobial drug, 11 metal component, 12,13 antimicrobial peptide, 8 polycation, 14 or ionic liquid 15 to enhance the antimicrobial ability. Xiang et al 12 used mussel-inspired catechol/amino chemistry to immobilize zwitterionic AgNPs on cotton gauze, and the sustained release of Ag + could give the modied cotton gauze excellent bactericidal activity. Gomes et al 8 incorporated different kinds of antimicrobial peptides into polyelectrolyte multilayer lms over cotton gauzes, and the antimicrobial peptides could provide higher antimicrobial effects in comparison with the controls.…”

Section: Introductionmentioning

confidence: 99%

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Synthesis of photothermal antimicrobial cotton gauze using AuNPs as photothermal transduction agents

Cao

Wei

et al. 2021

RSC Adv.

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Mussel-inspired immobilization of zwitterionic silver nanoparticles toward antibacterial cotton gauze for promoting wound healing

Cited by 114 publications

References 51 publications

Aqueous Modification of Chitosan with Itaconic Acid to Produce Strong Oxygen Barrier Film

Aqueous Modification of Chitosan with Itaconic Acid to Produce Strong Oxygen Barrier Film

Biofilms in Surgical Site Infections: Recent Advances and Novel Prevention and Eradication Strategies

Synthesis of photothermal antimicrobial cotton gauze using AuNPs as photothermal transduction agents

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