Mycotoxin detoxification of food by lactic acid bacteria

Abstract

Today, a few hundred mycotoxins have been identified and the number is rising. Mycotoxin detoxification of food and feed has been a technically uphill task for the industry. In the twenty-first century, the public demand is healthy food with minimum use of chemicals and preservatives. Among all the fungal inhibition and mycotoxin detoxification methods so far developed for food, biopreservation and biodetoxification have been found safe and reliable. Nowadays, lactic acid bacteria (LAB) are of great interest as biological additives in food owing to their Generally Recognized as Safe (GRAS) classification and mycotoxin detoxification capability. The occurrence of fungul growth in the food chain can lead to health problems such as mycotoxicosis and cancer to humans due to producing mycotoxins such as aflatoxins. Biopreservation is among the safest and most reliable methods for inhibition of fungi in food. This review highlights the great potential of LAB as biodetoxificant by summarizing various reported detoxification activities of LAB against fungal mycotoxins released into foods. Mechanisms of mycotoxin detoxification, also the inherent and environmental factors affecting detoxifying properties of LAB are also covered.

Characterization of Lactic Acid Bacteria from Fermented Fish (<i>pla-paeng-daeng</i>) and Their Cholesterol-lowering and Immunomodulatory Effects

“…They are used as probiotics in several Asian fermented foods (Ngasotter et al, 2020). Some LAB are generally regarded as safe (GRAS) microorganisms (Nasrollahzadeh et al, 2022). Previous studies suggested the beneficial effects of probiotics as part of a healthy diet in addition to their health-promoting effects, such as reductions in cholesterol and immunomodulation (Ohashi and Ushida, 2009;Angmo et al, 2016).…”

Brazilian Table Olives: A Source of Lactic Acid Bacteria with Antimycotoxigenic and Antifungal Activity

“…Typically, the mycotoxins adhere to the peptidoglycan structure of LAB cell walls, reducing their bioavailability, and consequently their toxicity since it prevents their intestinal absorption. Nonetheless, this phenomenon is strain-specific once different strains of the same species may have different bind capacities for specific mycotoxins [ 61 ]. Several LAB have been reported to be capable of binding PAT [ 15 , 62 ], OTA [ 63 ], and AFB1 [ 63 , 64 ].…”

Fusarium biocontrol: antagonism and mycotoxin elimination by lactic acid bacteria

“…Additionally, the combination of CDPs may display cooperative antibacterial effects whether antibiotics are present or absent. As an antimicrobial activity, CDPs may prevent the synthesis of ergosterol, change the osmotic balance, make the mold membrane porous, reduce mycelial growth, and alter the nuclear DNA’s functional and structural characteristics ( Kwak et al, 2014 ; Sellamani et al, 2016 ; Nasrollahzadeh et al, 2022b ). Dal Bello et al (2007) found that cyclo(L-Phe L-Pro) and cyclo(L-Leu-L-Pro) produced by L. plantarum FST1.7 have antifungal activity against F. culmorum and F. graminearum .…”