N-Halo Derivatives V: Comparative Antimicrobial Activity of Soft N-Chloramine Systems

N-Halo Derivatives IV: Synthesis of Low Chlorine Potential Soft N-Chloramine Systems

“…More importantly, VIIIc-VIIIf provide an opportunity for comparing the effect of a localized positive charge in the N-chloramine on its antimicrobial activity. With the preparation of a number of low chlorine potential, soft N-chloramine systems containing nitrogen-chlorine bonds of different polarity accomplished, comparative antimicrobial activity studies for these systems were initiated (11). Anal.-Calc.…”

Kinetics of N‐bromination of 2‐oxazolidinone

“…In the reaction with NBA, both 4 affords a value of 0.10 ± 0.02 for the overall equilibrium constant of this reaction at 25…”

“…4 [H + ] at the working pH, and given the abovenoted assumption concerning K 5 , Eq. (7) implies that a plot of the slope (k bwd = slope) against (1/[H + ]) is in fact, within experimental error, a straight line through the origin.…”

“…N -Halo-2-oxazolidinones [1,2] form polymers that can be used as coatings on plastics, glass and synthetic fibres [3], and the monomers can be used as disinfectants [4][5][6][7][8][9]. Although certain organisms are quite resistant to the most thoroughly studied chloro compound, 3-chloro-4,4-dimethyl-2-oxazolidinone [10] does have advantages as an auxiliary biocide, especially for disinfection of minor water supplies: it is an easily stored powder, and its relative stability ensures sustained action.…”

Chemical Properties of N-Chlorotaurine Sodium, a Key Compound in the Human Defence System

“…d This assertion concerns only the free N-chloroamino acids, while the N-chloro derivatives of diverse esters of α-aminoisobutyric acid turned out to be sufficiently stable to be synthesised [21].…”