Nanocarriers based novel and effective drug delivery system

MicroRNA-nanoparticles against cancer: Opportunities and challenges for personalized medicine

“…Inorganic NPs are less toxic and more stable than organic nanocarriers and can protect drugs from degradation allowing a gradual release. 72 Solid nanocarriers, particularly iron oxide NPs, formed by an organic core as Fe 3 O 4 with a biocompatible polymer, are often used as inorganic biosensors in magnetic resonance imaging (MRI). 73 Solid gold NPs display different features including high biocompatibility and permeability, thus allowing to reach the proper site of action and release high concentrations of the drug.…”

“…The peculiar composition allows the binding of several water-soluble and hydrophobic drugs, ensuring high efficiency as a nanocarrier. 72 To date, different NPs are used for multiple purposes based on their specific properties. Polymeric nanoparticles (PNPs) are the most common organic NPs able to include compounds in a polymeric matrix consisting in poly lactic glycolic acid (PLGA) or chitosan.…”

Recent trends in macromolecule-conjugated hybrid quantum dots for cancer theranostic applications

“…The theranostic technique in cancer treatment may use the simultaneous delivery of chemotherapeutics and photolytic chemicals for deep tumor penetration. 67 Both in vitro and in vivo studies have been conducted on the HQDs for cancer therapy. The most effective non-invasive cancer treatment modality with little adverse effects is PDT.…”

Research Advances of Engineered Exosomes as Drug Delivery Carrier

“…In the past decades, various synthetic nanocarriers have been developed to enhance therapeutic efficacy, such as liposomes, micelles, carbon nanotubes, and dendrimers . Moreover, various functionalized modifications of nanocarriers have been used to improve the key properties of drug delivery . For example, they extended circulation time in vivo , stimulated response, and improved drug loading.…”

“…5 Moreover, various functionalized modifications of nanocarriers have been used to improve the key properties of drug delivery. 6 For example, they extended circulation time in vivo, stimulated response, and improved drug loading. However, synthetic drug delivery systems still have some limitations.…”