Nanostructured hydroxyapatite as filler for methacrylate‐based root canal sealers

Collares, Fabrício Mezzomo; Leitune, Vicente Castelo Branco; Rostirolla, Flávia Veronezi; Trommer, Rafael Mello; Bergmann, Carlos Pérez; Samuel, Susana Maria Werner

doi:10.1111/j.1365-2591.2011.01948.x

Cited by 51 publications

(34 citation statements)

References 27 publications

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“…For example, toothpastes containing nanodimensional apatite could promote a partial remineralization of demineralized enamel [680][681][682][683][684], as well as possess some whitening effect [685]. Furthermore, nano-sized HA might be added to methacrylate-based root canal sealers [686], as well as to a fluoride-containing mouth rinse [687]. A remineralization potential of sports drink, containing nano-sized HA, was also investigated [688,689].…”

Section: Dental Applicationsmentioning

confidence: 99%

Nanodimensional and Nanocrystalline Calcium Orthophosphates

Dorozhkin¹

2012

AJBE

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Nano-sized particles and crystals play an important role in the formation of calcified tissues of various animals. For example, nano-sized and nanocrystalline calcium orthophosphates in the form of apatites of biological origin represent the basic inorganic building blocks of bones and teeth of mammals. Namely, according the recent developments in biomineralization, tens to hundreds nanodimensional crystals of a biological apatite are self-assembled into these complex structures. This process occurs under a strict control by bioorganic matrixes. Furthermore, both a greater viability and a better proliferation of various types of cells have been detected on smaller crystals of calcium orthophosphates. Thus, the nano-sized and nanocrystalline forms of calcium orthophosphates have a great potential to revolutionize the hard tissue-engineering field, starting from bone repair and augmentation to controlled drug delivery systems. This review reports on current state of the art and recent developments on the subject, starting from synthesis and characterization to biomedical and clinical applications. Furthermore, the review also discusses possible directions for future research and development.

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Section: Dental Applicationsmentioning

confidence: 99%

Nanodimensional and Nanocrystalline Calcium Orthophosphates

Dorozhkin¹

2012

AJBE

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“…CQ and EDAB were added at 1 mol% to all groups, according to the monomer moles. Nanostructure hydroxyapatite (HA nano ) was produced according to previous studies [10][11][12]. HA nano was added at the following two concentrations: 0 and 2 wt%.…”

Section: Formulationmentioning

confidence: 99%

Interface evaluation of experimental dental adhesives with nanostructured hydroxyapatite incorporation

et al. 2014

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The aim of this study was to evaluate the adhesive interface with dentin of an experimental adhesive resin with nanostructured hydroxyapatite addition. The organic phase of the adhesive resin was produced by mixing 50 wt.% Bis-GMA, 25 wt.% TEGDMA and 25 wt.% HEMA. CQ and EDAB were added at 1 mol% to all groups, according to the monomer moles. HA nano was added at the following two concentrations: 0 and 2 wt%. One commercial adhesive system was used as control. Nine lower incisor bovine teeth were used to produce interfaces of adhesive resin and dentin. Tooth slices were analysed using the following micro-Raman parameters: a 100 mW diode laser with 785 nm wavelength and spectral resolution of~3-5 cm -1 . One-dimensional mapping was performed over a 150 μm line across the adhesive-dentine interface at 1 μm intervals using a computerized XYZ stage. These areas covered the composite resin, adhesive layer, hybrid layer, partially demineralised and un-affected dentine and were visualised and focused at x500 magnification. Raman analysis showed the penetration of experimental and commercial adhesive systems into dentin. HA nano was observed into the hybrid layer. Based on results of the present study, is possible to observe resin and nanostructured hydroxyapatite penetration at the hybrid layer.

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“…[72122] Properties like antimicrobial activity, radiopacity, flow, film thickness and cytotoxicity have been evaluated in various studies. We could not found any published reports on sealing ability of nano-materials as sealer in root canal therapy to make comparisons.…”

Section: Discussionmentioning

confidence: 99%

Zinc oxide nano-particles as sealer in endodontics and its sealing ability

et al. 2014

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Aims:The aim of this study was to evaluate the sealing ability of new experimental nano-ZOE-based sealer.Settings and Design:Three types of nano-ZOE-based sealer (calcined at different temperatures of 500, 600 and 700°C) with two other commercially available sealers (AH26 and micro-sized zinc oxide eugenol sealer) were used.Materials and Methods:Zinc oxide nano-particles were synthesized by a modified sol-gel method. The structure and morphology of the prepared powders were characterized using x-ray diffraction (XRD) and transmission electron microscopy (TEM) techniques. The instrumented canals of 60 single-rooted teeth were divided into five groups (n = 10), with the remaining ten used as controls. The canals were filled with gutta-percha using one of the materials mentioned above as sealer. After 3, 45 and 90 days, the samples were connected to a fluid filtration system.Statistical Analysis Used:The data were analyzed using Student's t-test.Results:The XRD patterns and TEM images revealed that all the synthesized powders had hexagonal wurtzite structures with an average particle size of about 30-60 nm at different calcination temperatures. Microleakage in AH26 groups was significantly more than that in three groups of ZnO nano-particles at all the three evaluation intervals. Apical microleakage of ZnO micro-powders was significantly more than that of all the materials, but the sealing ability of ZnO nano-powder sealers did not differ significantly.Conclusion:The results of this study showed that the synthesized ZnO nano-powder sealers are suitable for use as a nano-sealer in root canal therapy to prevent leakage; however, further studies should be carried out to verify their safety.

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Nanostructured hydroxyapatite as filler for methacrylate‐based root canal sealers

Abstract: The addition of up to 40% HA(nano) to root canal sealers did not alter their radiopacity and film thickness.

Cited by 51 publications

References 27 publications

Nanodimensional and Nanocrystalline Calcium Orthophosphates

Nanodimensional and Nanocrystalline Calcium Orthophosphates

Interface evaluation of experimental dental adhesives with nanostructured hydroxyapatite incorporation

Zinc oxide nano-particles as sealer in endodontics and its sealing ability

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