Natural Oils for Skin-Barrier Repair: Ancient Compounds Now Backed by Modern Science

Vaughn, Alexandra R.; Clark, Ashley K.; Sivamani, Raja K; Shi, Vivian Y.

doi:10.1007/s40257-017-0301-1

Cited by 133 publications

(130 citation statements)

References 69 publications

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“…Almond oil, soybean oil, avocado oil and coconut oil [115] have a strong occlusive effect similar to that of paraffin oil [116]. Table 7 Selection of oils based on their linoleic acid content [111][112][113].…”

Section: Many Oils Also Differ In Their Vitamin and Phytosterol Contementioning

confidence: 99%

Diagnosis and treatment of xerosis cutis – a position paper

Augustin

Wilsmann‐Theis²,

Körber³

et al. 2019

J Deutsche Derma Gesell

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Summary Background and rationale Xerosis cutis (also referred to as xeroderma, dry skin, asteatosis) affects more than 10 million individuals in Germany. It is among the most common dermatological diagnoses and a cardinal symptom of many dermatological, internal and neurological diseases. Even though it has been established that basic skin care plays a significant role in the management of patients with xerosis cutis, there are as yet no evidence‐based algorithms for diagnosis and treatment. Objective The present position paper provides physicians across all specialties with a practical, symptom‐based approach to the prevention, diagnosis and treatment of xerosis cutis. Methods Within a structured decision‐making process, a panel of experienced dermatologists first defined questions relevant to everyday clinical practice, which were then addressed by a systematic review of the literature. Based on the evidence available as well as expert consensus, diagnostic and treatment algorithms were subsequently developed and agreed upon. Results Xerosis cutis is generally diagnosed on clinical grounds. Possible trigger factors must be avoided, and comorbidities should be adequately and specifically treated. Suitable skin care products should be chosen with a view to improving skin hydration and restoring its barrier function. They should therefore contain both rehydrating and lipid‐replenishing components. The “drier” the skin appears, the greater the lipid content should be (preferably using water‐in‐oil formulations). The choice of ingredients is based on a patient's individual symptoms, such as scaling (e.g., urea), fissures/rhagades (e.g., urea or dexpanthenol), erythema (e.g., licochalcone A) and pruritus (e.g., polidocanol). Other factors to be considered include the site affected and patient age. Ingredients or rather combinations thereof for which there is good clinical evidence should be preferentially used. The best evidence by far is available for urea, whose efficacy in the treatment of xerosis is further enhanced by combining it with other natural moisturizing components and ceramides. The “xerosimeter” is a tool developed in an effort to facilitate patient management and for training purposes. It not only includes practical tools for diagnosis and follow‐up but also a classification of ingredients and a structured treatment algorithm. Conclusion The structured symptom‐ and evidence‐based approach proposed herein contains a road map for diagnosis and treatment of xerosis cutis. It aims to raise awareness in terms of prevention and early treatment of this condition and may thus improve quality of life and prevent potential sequelae.

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Section: Many Oils Also Differ In Their Vitamin and Phytosterol Contementioning

confidence: 99%

Diagnosis and treatment of xerosis cutis – a position paper

Augustin

Wilsmann‐Theis²,

Körber³

et al. 2019

J Deutsche Derma Gesell

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“…They affect phases of the wound‐healing process through their bacteriostatic, antimicrobial, anti‐inflammatory, and antioxidative activities and by promoting cell proliferation, increasing collagen synthesis, stimulating dermal reconstruction, and repairing the skin's lipid barrier function (Cornily et al, ; de Oliveira et al, ; Lamaud, Huc, & Wepierre, ; Lewinska, Zebrowski, Duda, Gorka, & Wnuk, ; T.‐K. Lin, Zhong, & Santiago, ; Mandawgade & Patravale, ; Nasopoulou, Karantonis, Detopoulou, Demopoulos, & Zabetakis, ; Shinagawa, de Santana, Torres, & Mancini‐Filho, ; Vaughn, Clark, Sivamani, & Shi, ). Fatty acids were shown to play major role in the wound‐healing process (Cardoso, Souza, Ferro, Favoreto, & Pena, ; de Oliveira et al, ; McDaniel, Belury, Ahijevych, & Blakely, ).…”

Section: Introductionmentioning

confidence: 99%

Vegetable butters and oils in skin wound healing: Scientific evidence for new opportunities in dermatology

Poljšak

Kreft

Glavač

2019

Phytotherapy Research

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The use of vegetable butters and oils shows promising results in the treatment of skin wounds, as they have an effective impact on the phases of the wound-healing process through their antimicrobial, anti-inflammatory, and antioxidative activities and by promoting cell proliferation, increasing collagen synthesis, stimulating dermal reconstruction, and repairing the skin's lipid barrier function.In this article, in vitro and in vivo studies of argan (Argania spinosa), avocado (Persea americana), black cumin (Nigella sativa), calophyllum (Calophyllum inophyllum), coconut (Cocos nucifera), cranberry (Vaccinium macrocarpon), grape (Vitis vinifera), green coffee (Coffea arabica), lentisk (Pistacia lentiscus), linseed (Linum usitatissimum), lucuma (Pouteria lucuma), mango (Mangifera indica), olive (Olea europaea), pomegranate (Punica granatum), pumpkin (Cucurbita pepo), rapeseed (Brassica napus), sea buckthorn (Hippophae rhamnoides), and sunflower (Helianthus annuus) oils were reviewed. In many cases, vegetable oils proved to be more effective than synthetic wound-healing compounds used as controls.The fatty-acid components of vegetable oils are assumed to play a major role in the wound-healing process, in particular polyunsaturated fatty acids such as linoleic acid.Evidence shows that oils with a higher linoleic to oleic acid ratio are more effective for lipid barrier repair. However, in depth studies are needed to gain knowledge about vegetable oils' effects on the skin and vice versa. KEYWORDSfatty acids, skinskin woundskin wound healingvegetable buttersvegetable oils

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“…However, for skin care products, quince seed oil is well suited because of the high content of linoleic acid . Oils with a higher linoleic acid/oleic acid ratio have better barrier repair potential …”

Section: Resultsmentioning

confidence: 99%

The Fatty Acid Composition and Quality of Oils from Post‐Industrial Waste of Quince Chaenomeles japonica

Urbanavičiūtė

Rubinskienė

Viškelis

2019

Chemistry & Biodiversity

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In the food industry, quince seeds are discarded as waste in the production process. Their use therefore creates added value and opens up the possibility of using no‐waste processing technologies. Three types of waste were investigated: after juicing, after the manufacture of puree and syrup. The results showed that the yield of quince seeds (Chaenomeles japonica (Thunb.) Lindl. ex Spach from waste left after different production methods varies from 29.8 to 38.3 %. The cold pressed oil yield ranges from 4.9±0.03 to 7.1±0.06 %. The oil yield obtained by Soxhlet extraction varies from 14.6±0.64 to 17.3±0.9 %. Unsaturated fatty acid, especially polyunsaturated fatty acid is predominant in quince seed oil. The linoleic acid content of the quince seed oils was between 47.12 % and 58.49 % of the total fatty acids. The fatty acid composition of oils from post‐industrial waste is more appropriate in the skin care industry than in the food industry because of the high ratio of omega‐6/omega‐3 and high linoleic acid content.

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Natural Oils for Skin-Barrier Repair: Ancient Compounds Now Backed by Modern Science

Cited by 133 publications

References 69 publications

Diagnosis and treatment of xerosis cutis – a position paper

Diagnosis and treatment of xerosis cutis – a position paper

Vegetable butters and oils in skin wound healing: Scientific evidence for new opportunities in dermatology

The Fatty Acid Composition and Quality of Oils from Post‐Industrial Waste of Quince Chaenomeles japonica

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