In the present work, we investigated the mechanical properties (including hardness, fracture toughness, brittleness index and yield strength) of Nd 0.03 Gd 0.93 Y 2.04 Sc 2 Ga 3 O 12 (Nd:GYSGG) laser crystal using Vickers microhardness tester, for the first time. The defects morphology of Nd:GYSGG crystal were investigated by using chemical etching method with phosphoric acid etchant. The absorption spectrum of Nd:GYSGG from 300 to 2800 nm was measured at room temperature and the absorption peaks were assigned. The fluorescence lifetime of the 4 F 3/2 → 4 I 11/2 transition of Nd 3+ in GYSGG is fitted to be 221.3 μs. The three Judd-Ofelt intense parameters 2, 4, 6 were calculated to be 0.329 × 10 −20 cm 2 , 2.761 × 10 −20 cm 2 and 4.222 × 10 −20 cm 2 , respectively. All these demonstrate that Nd:GYSGG crystal is a good candidate laser material.