Neonatal Hypoglycemia - Current Concepts

Fernández, B. Álvarez; Pérez, Irene Cuadrado

doi:10.5772/21448

Cited by 2 publications

(3 citation statements)

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“…Transient hypoglycaemia is seen in less than 3-5 days; persistent hypoglycaemia is seen in more than 5-7 days [22] . The reasons for persitent hypoglycaemia are shown in Table 2 [23] .…”

Section: Etiology Of Hypoglycaemia and Risk Factorsmentioning

confidence: 99%

“…The reasons for persitent hypoglycaemia are shown in Table 2 [23] . The reasons for transient neonatal hypoglycaemia are [22,24,25] : (1) Inadequate glucose production: Prematurity; Intrauterine growth restriction; Postmaturity; Sepsis; Perinatal asphyxia. (2) Excessive glucose use: Infants of diabetic mothers; Intrauterine growth restriction; Perinatal asphyxia; Sepsis; Cyanotic heart disease or congestive heart disease; Erythroblastosis fetalis; High umbilical artery catheter; Polycythemia; Drugs used by the mother (betasympathomimetics, oral antidiabetics); Large for gestational age; Infant of toxemic or preeclamptic mothers; Hypothermia; Interruption of intravenous fluid fast.…”

Section: Etiology Of Hypoglycaemia and Risk Factorsmentioning

confidence: 99%

“…Convulsion is commonly seen after elongated or recurrent hypoglycaemia and rarely seen in the early periods; it is correlated with the severity of the hypoglycaemia. Jitteriness is one of the most common symptoms of hypoglycaemia, it is not suitable to determine hypoglycaemia because it may be seen in healthy term infants [22,24] .…”

Section: The Symptoms Of Hypoglycaemia In the Newborn Periodmentioning

confidence: 99%

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A Perspective on Neurological Aspects of Neonatal Hypoglycaemia

Hosagasi

Aydın

2016

International Journal of Neurology Research

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Cerebral metabolism is mainly dependent upon glucose utilization. In newborn infants, low blood glucose levels cause to neuronal and glial cell death, and hence associated with long-term neurodevelopmental handicaps. Occipital and parietal lobes are most severely affected regions of the brain on imaging techniques in infants suffered from brain damage as a result of neonatal hypoglycaemia. On neurodevelopment follow up, the mental and psychomotor developmental indexes of the children who suffered from hypoglycaemia during newborn period are significantly low. Hence, early diagnosis and treatment of neonatal hypoglycaemia is mandatory to prevent the long-term neurological sequelae.

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“…Transient hypoglycaemia is seen in less than 3-5 days; persistent hypoglycaemia is seen in more than 5-7 days [22] . The reasons for persitent hypoglycaemia are shown in Table 2 [23] .…”

Section: Etiology Of Hypoglycaemia and Risk Factorsmentioning

confidence: 99%

Section: Etiology Of Hypoglycaemia and Risk Factorsmentioning

confidence: 99%

Section: The Symptoms Of Hypoglycaemia In the Newborn Periodmentioning

confidence: 99%

See 1 more Smart Citation

A Perspective on Neurological Aspects of Neonatal Hypoglycaemia

Hosagasi

Aydın

2016

International Journal of Neurology Research

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Hubungan Kadar Albumin Plasma Dan Gula Darah Dengan Sepsis Neonatorum

Wowor

Rompis

Wilar

2013

eBM

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Abstract. Sepsis is the most leading cause of morbidity and mortality in neonates. In sepsis, the proinflammatory cytokines realeasing leads to disruption of plasma albumin and blood glucose levels. This study aim to analyze the relationship of plasma albumin and blood sugar levels with neonatal sepsis. Prospective observational analytic studies conducted on suspected sepsis neonates at Pediatrics Department Sub Division Neonatology RSUP Prof.Kandou Manado. Diagnosis of sepsis based on clinical symptoms and laboratory tests. Subjects are grouped into two groups of neonatal sepsis and non-neonatal sepsis group (control group). Plasma albumin and blood glucose level examined, then statistically analyzed. The statistical analysis used was Pearson Chi-Square correlation and Fisher Exact. The data were processed using SPSS 21. The results of this study indicate that hypoalbuminemia was found in 12 (75%) of 16 neonatal sepsis subject, whereas in non-neonatal sepsis only found 5 (22,7%) of 22 non-sepsis subjects. Statistically there is a highly significant difference (p=0,001). For the impaired blood glucose (both hypoglycemia or hyperglycemia) there is no significant difference between the two groups (p=0,466).Conclusion: There is a highly significant relationship between hypoalbuminemia with neonatal sepsis. There was no significant correlation between abnormal blood glucose levels with neonatal sepsis. Keywords: neonatal sepsis, plasma albumin levels, blood glucose levels Abstrak.Sepsis merupakan penyebab morbiditas dan mortalitas terbanyak pada neonatus. Pada sepsis terjadi pelepasan sitokin proinflamasi yang memicu terjadinya gangguan kadar albumin plasma dan kadar glukosa darah.Menganalisis hubungan kadar albumin plasma dan kadar gula darah dengan sepsis neonatorum.Penelitian analitik observasional prospektif dilakukanpada tersangka sepsis neonatorum yang dirawat di bagian Ilmu Kesehatan Anak Sub Bagian Neonati RSUP Prof. Dr. R.D. Kandou Manado. Diagnosis sepsis berdasarkan gejala klinik dan pemeriksaan laboratorium. Subyek penelitian dikelompokkan menjadi kelompok sepsis neonatorum dan kelompok non sepsis neonatorum (kelompok kontrol). Dilakukan pemeriksaan kadar albumin plasma dan glukosa darah, kemudian dianalasis secara statistik. Analisis statistik yang digunakan adalah uji korelasi Pearson Chi-Square dan uji Fisher Exact. Data diolah dengan menggunakan program SPSS 21.Hasil penelitian menunjukkan bahwa hipoalbuminemia ditemukan pada 12 (75%) dari 16 penderita sepsis neonatorum, sedangkan pada penderita non sepsis hanya ditemukan 5 (22,7%) dari 22 penderita non sepsis. Secara statistik terdapat perbedaan yang sangat bermakna (p=0,001). sedangkan gangguan glukosa darah (baik hipoglikemia maupun hiperglikemia) tidak terdapat perbedaan yang bermaknsa antara kedua kelompok (p=0,466).Simpulan:Terdapat hubungan yang sangat bermakna antara hipoalbuminemia dengan sepsis neonatorum. Tidak terdapat hubungan yang bermakna antara kadar gula darah abnormal dengan sepsis neonatorum. Kata Kunci:sepsis neonatorum, kadar albumin plasma, kadar glukosa darah

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Neonatal Hypoglycemia - Current Concepts

Cited by 2 publications

References 25 publications

A Perspective on Neurological Aspects of Neonatal Hypoglycaemia

A Perspective on Neurological Aspects of Neonatal Hypoglycaemia

Hubungan Kadar Albumin Plasma Dan Gula Darah Dengan Sepsis Neonatorum

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