Neuere chemische und biochemische Entwicklungen auf dem Vitamin‐B<sub>12</sub>‐Gebiet

Bernhauer, Konrad; Müller, Otto; Wagner, Fritz

doi:10.1002/ange.19630752302

Cited by 36 publications

(10 citation statements)

References 66 publications

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“…Their ionophoretic mobilities at pH 9 (Table 11) indicate one and more negative charges on the molecules, probably due to free carboxylic acid groups on the corrin nucleus. Such compounds are assumed to be precursers of cobinamide coenzyme by Bernhauer et al (1962Bernhauer et al ( , 1963.…”

Section: Discussionmentioning

confidence: 99%

Corrinoid Compounds of Methanobacillus omelianskii. I. Fractionation of the Corrinoid Compounds and Identification of Factor III and Factor III Coenzyme^*

Lezius¹,

Barker²

1965

Biochemistry

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The corrinoid compounds from an extract of M. omelianskii were separated into ten components by chromatographic methods. 5-Hydroxybenzimidazolylcobamide and its co-5 '-deoxyadenosyl derivative (Factor I11 coenzyme) are the most abundant corrinoid compounds in this organism, accounting for 31 and 23 z, respectively, of the total vitamin Biz activity T he possible participation of a vitamin B12 coenzyme in the metabolism of one-carbon compounds of Methanococcus vannielii and Methanobacillus omelianskii was first suggested by Stadtman (1960) because of the high level of cobamide coenzymes in these organisms. The recent finding of Blaylock and Stadtman (1963) and Wolin et al. (1963) that the methyl group of

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Section: Discussionmentioning

confidence: 99%

Corrinoid Compounds of Methanobacillus omelianskii. I. Fractionation of the Corrinoid Compounds and Identification of Factor III and Factor III Coenzyme^*

Lezius¹,

Barker²

1965

Biochemistry

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“…Corrinoid-Co-Sulfonsauren treten bei Reinigungsoperationen an Corrinoiden, insbesondere ihren Hydroxo(Aqu0)-Formen, haufig als Nebenprodukte auf, vor allem in Industrie-Gebieten infolge des hohen SOz-Gehaltes der Luft. Auch mit Sulfit verunreinigtes Phenol kann wahrend der Phenolextraktion zur Bildung dieser Verbindungen fuhren (50).…”

Section: Corrinoide Mit Kobalt-schwefel-bindungunclassified

“…Nachfolgend wird nur die neueste Entwicklung auf dem Gebiet der %hemie und Biochemie der Corrinoide* und ihrer Coenrym-Formen dargestellt (a. zusammenfassende Literatur [1][2][3][4][5][6][7][8][9][10][11], wahrend die medizinischen und physiologischen Fortschritte auf diesem Gebiet nicht bertlcksichtigt werden konnen. Der einfachste Grundkorper, * der bereits alle wesentlichen Strukturmerkmale der Corrinoide besitzt, ist die Cobyrinsaure (111).…”

Section: Introductionunclassified

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Fortschritte Auf Dem Vitamin B ₁₂ ‐Gebiet

Bernhauer

Müller

Wagner

1964

Advances in Enzymology - And Related Areas of Molecular Biology

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“…Initially developed as curiosities, they are now of great importance since they are recognized to play crucial roles in living systems (notably vitamin B12 [1]) and in all catalyzed transformations of organic substrates that result in the functionalization of sp 3 -hybridized carbon atoms [2].…”

Section: Introductionmentioning

confidence: 99%

Homolytically weak metal-carbon bonds make robust controlled radical polymerizations systems for “less-activated monomers”

Fliedel

Poli

2019

Journal of Organometallic Chemistry

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This article is an account of work, mostly carried out in the authors' laboratory, on the use of organometallic compounds with homolytically fragile metal-carbon bonds as dormant species in the controlled radical polymerization of a variety of monomers in what is now universally called "organometallic-mediated radical polymerization" (OMRP). The article retraces a brief history of OMRP, shows how it can potentially intervene in every radical polymerization process based on atom transfer (ATRP), which is a more popular controlling method where the metal plays a catalytic role, and how it can be in competition with another catalyzed process involving chain transfer to monomer (CCT). It highlights the challenges of controlled radical polymerization in the area of the "less activated monomers" (LAMs) and particularly the problem of the monomer addition errors, demonstrating how ligand engineering and coordination chemistry constitute additional handles, not available to other moderating species, providing acceptable ad hoc solutions. It details how OMRP could achieve unsurpassed levels of control for two specific monomers: vinyl acetate (VAc) and vinylidene fluoride (VDF). Finally, it lays the principles for the development of efficient chain transfer catalysts for less activated monomers.

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Neuere chemische und biochemische Entwicklungen auf dem Vitamin‐B₁₂‐Gebiet

Cited by 36 publications

References 66 publications

Corrinoid Compounds of Methanobacillus omelianskii. I. Fractionation of the Corrinoid Compounds and Identification of Factor III and Factor III Coenzyme^*

Corrinoid Compounds of Methanobacillus omelianskii. I. Fractionation of the Corrinoid Compounds and Identification of Factor III and Factor III Coenzyme^*

Fortschritte Auf Dem Vitamin B ₁₂ ‐Gebiet

Homolytically weak metal-carbon bonds make robust controlled radical polymerizations systems for “less-activated monomers”

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Neuere chemische und biochemische Entwicklungen auf dem Vitamin‐B12‐Gebiet

Cited by 36 publications

References 66 publications

Corrinoid Compounds of Methanobacillus omelianskii. I. Fractionation of the Corrinoid Compounds and Identification of Factor III and Factor III Coenzyme*

Corrinoid Compounds of Methanobacillus omelianskii. I. Fractionation of the Corrinoid Compounds and Identification of Factor III and Factor III Coenzyme*

Fortschritte Auf Dem Vitamin B 12 ‐Gebiet

Homolytically weak metal-carbon bonds make robust controlled radical polymerizations systems for “less-activated monomers”

Contact Info

Product

Resources

About

Neuere chemische und biochemische Entwicklungen auf dem Vitamin‐B₁₂‐Gebiet

Corrinoid Compounds of Methanobacillus omelianskii. I. Fractionation of the Corrinoid Compounds and Identification of Factor III and Factor III Coenzyme^*

Corrinoid Compounds of Methanobacillus omelianskii. I. Fractionation of the Corrinoid Compounds and Identification of Factor III and Factor III Coenzyme^*

Fortschritte Auf Dem Vitamin B ₁₂ ‐Gebiet