1998
DOI: 10.1067/msy.1998.86363
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Neuroendocrine tumor of the common hepatic duct: A rare cause of extrahepatic jaundice in adolescence

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Cited by 5 publications
(5 citation statements)
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“…The peak of expression of the plasmid in vivo was determined to occur on day 3 (Figure 4A), which is consistent with the in vitro data (Figure 3B). Although most of the previous studies showed that less than 10% of the plasmid can reach the general circulation after direct plasmid intramuscular injection [36], [37], it was reported that plasmid can be detected by PCR up to 1 year in mice [38]. Here, we showed that the use of ex vivo transfection has substantially decreased this time.…”
Section: Discussionmentioning
confidence: 56%
“…The peak of expression of the plasmid in vivo was determined to occur on day 3 (Figure 4A), which is consistent with the in vitro data (Figure 3B). Although most of the previous studies showed that less than 10% of the plasmid can reach the general circulation after direct plasmid intramuscular injection [36], [37], it was reported that plasmid can be detected by PCR up to 1 year in mice [38]. Here, we showed that the use of ex vivo transfection has substantially decreased this time.…”
Section: Discussionmentioning
confidence: 56%
“…In our review of the literature, we found that in 2 of the 4 reported cases (Table 1), local tumor resection with Rouxen-Y hepaticojejunostomy was performed with no recurrences described [5,7]. We think that, in cases of children with well localized tumors, excision without a peancreaticoduodenectomy might be safely performed.…”
Section: Discussionmentioning
confidence: 90%
“…Our literature search revealed that 51 cases of neuroendocrine tumors localized to the extra hepatic bile duct had been reported with four of those presenting in children (3 girls, 1 boy; 12-15 years of age) [4][5][6][7][8]. To our knowledge, we present the second pediatric case of a neuroendocrine tumor located on the distal common hepatic duct at this early age.…”
mentioning
confidence: 83%
“…The tumor was located at the common hepatic duct in 13 (52%), followed by common hepatic duct bifurcation in 8 (32%). There was no metastasis in 18 cases (72%), whereas lymph node metastasis was observed in 4 cases (16%) (13,14,19,27) and liver metastasis in 3 cases (12%) (11,23,25). The most common operative procedure was extrahepatic bile duct resection in 18 (72%) patients, followed by choledochotomy and tumor resection in 2 (8%) patients.…”
Section: Discussion and Literature Reviewmentioning
confidence: 99%