Neurological involvement in visceral leishmaniasis: case report

Diniz, Lílian Martins Oliveira; Duani, Helena; Freitas, Camila Rodrigues; Figueiredo, Rosângela Maria; Xavier, Christovão Castro

doi:10.1590/s0037-86822010000600031

Cited by 20 publications

(14 citation statements)

References 6 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In Brazil, a case report showed that a child heavily parasitized by Leishmania presented neurological signs as the first symptoms of VL. This patient, presenting abnormal movements characterized by tremors in the hands and head, and myoclonic movements on his face, showed a diffuse reduction of the frontal lobes and cerebral atrophy in brain images analyses . Other few well‐documented reports refer mainly to meningoencephalitis and ocular manifestations .…”

Section: Neurological Alterations In Human Visceral Leishmaniasismentioning

confidence: 67%

Neurological disease in human and canine leishmaniasis – clinical features and immunopathogenesis

Maia

Monteiro

Gavioli

et al. 2015

Parasite Immunology

View full text Add to dashboard Cite

Leishmaniasis is a vectorborne disease caused by Leishmania protozoa, which is a major health problem and a neglected disease common in many regions of the world. Leishmania is an intracellular parasite transmitted by sand flies that causes clinical manifestations ranging from a severe and potentially fatal disease named visceral leishmaniasis to less severe but in many cases disfiguring diseases that mainly affect the skin or mucosal tissues, known as cutaneous leishmaniasis. Despite the detection of Leishmania parasites in the brain and cerebrospinal fluid of human patients and dogs, epidemiological data, as well as information about the mechanisms of central and peripheral nervous system alterations, are poorly described. This review is focused on the current knowledge about the neurological manifestations and immunopathogenic mechanisms in human patients and animals infected with Leishmania.

show abstract

Section: Neurological Alterations In Human Visceral Leishmaniasismentioning

confidence: 67%

Neurological disease in human and canine leishmaniasis – clinical features and immunopathogenesis

Maia

Monteiro

Gavioli

et al. 2015

Parasite Immunology

View full text Add to dashboard Cite

show abstract

“…Sensorimotor peripheral neuropathy occurred in 46% of patients with leishmaniasis in one series [35]. Nerve biopsy in patients with Leishmania-associated neuropathy did not reveal inflammation or direct parasitic nerve involvement [35,36], although perineural Leishmania amastigotes and inflammation have rarely been identified in infected patients without signs or symptoms of neuropathy [37,38]. A predisposition to Leishmania-associated neuropathy in patients with concurrent vitamin deficiency has been debated [35].…”

Section: Leishmaniasis (Leishmania Species)mentioning

confidence: 99%

Neurologic manifestations of the neglected tropical diseases

Berkowitz

Raibagkar

Pritt

et al. 2015

Journal of the Neurological Sciences

View full text Add to dashboard Cite

“…A leishmaniose visceral (LV) é transmitida ao homem por insetos vetores ou transmissores, conhecidos como flebotomíneos (Souto et al, 2013). A transmissão acontece quando uma fêmea infectada passa o protozoário a uma vítima sem a infecção, enquanto se alimenta de seu sangue (Diniz et al, 2010). É causada por espécies do gênero Leishmania, pertencentes ao complexo donovani.…”

Section: Introductionunclassified

Nova Estratégia De Biodetecção De Leishmaniose Baseada Em Filme Nanoestruturado Depolianilina

García¹,

Melo²,

Andrade³

et al. 2017

Anais Do 5º Encontro Brasileiro Para Inovação Terapêutica

View full text Add to dashboard Cite

RESUMO-A leishmaniose é uma zoonose largamente disseminada no Brasil. O presente trabalho tem como principal objetivo estudar o processo de eletropolimerização do sistema NPsFe 3 O 4 / Quit/PANI frente amostras de genoma e soro de cães infectados com leishmaniose. A avaliação do sistema foi realizada através da técnica eletroquímica de voltametria cíclica para caracterizar as propriedades elétricas do sistema NPsFe 3 O 4 / Quit/PANI-Primer Leish. Os resultados mostram que o sistema sensor foi capaz de reconhecer as amostras de genomas e de soro dos cães infectados, em várias concentrações, sendo observada uma diminuição da resposta amperométrica total do sistema. Mostrando assim que o sistema NPsFe 3 O 4 / Quit/PANI-Primer Leish é viável para detecção da leishmaniose. Palavras chave-biossensor, voltametria, impedância, leishmaniose ABSTRACT-Leishmaniasis is a widespread zoonosis in Brazil. The present work has as main objective to study the process of electropolymerization of the NPsFe 3 O 4 / Quit / PANI system against genome and serum samples from dogs infected with leishmaniasis. The evaluation of the system was performed by the electrochemical technique of cyclic voltammetry to characterize the electrical properties of the NPsFe 3 O 4 / Quit / PANI-PrimerLeish system. The results show that the sensor system was able to recognize the genomic and serum samples of the infected dogs at various concentrations, with a decrease in the total amperometric response of the system. Thus showing that the NPsFe 3 O 4 / Quit / PANI-PrimerLeish system is feasible for detection of leishmaniasis.

show abstract

Neurological involvement in visceral leishmaniasis: case report

Cited by 20 publications

References 6 publications

Neurological disease in human and canine leishmaniasis – clinical features and immunopathogenesis

Neurological disease in human and canine leishmaniasis – clinical features and immunopathogenesis

Neurologic manifestations of the neglected tropical diseases

Nova Estratégia De Biodetecção De Leishmaniose Baseada Em Filme Nanoestruturado Depolianilina

Contact Info

Product

Resources

About