New assay method for the determination of vinpocetine in human plasma by gas chromatography—mass spectrometry without transesterification caused by solvents

Determination of vinpocetine and its primary metabolite, apovincaminic acid, in rat plasma by liquid chromatography–tandem mass spectrometry

“…The pharmacokinetic investigations of VP have been conducted by direct mass fragmentography [10,11], HPLC [12][13][14][15], sensitive enzyme immunoassay [16], gas chromatography (GC) with nitrogen-phosphorus detection [17][18][19][20][21] and GC-MS methods [22][23][24][25][26][27]. Also, several methods have been developed for the determination of AVA.…”

Electrochemical Behavior of Vinpocetine at Carbon Paste Electrodes Modified with Calixarenes

“…Vinpocetine is used for treatment of cerebral blood-flow disorders, agerelated memory impairment, and atherosclerosis. For determination of vinpocetine, high-performance liquid chromatography, 20,21 gas chromatography, [22][23][24] spectrophotometry, 25 and enzyme immunoassay 26 were used. However, to date there is no analytical procedure described for voltammetric determination of vinpocetine.…”