New ceramides from the flower of Albizia julibrissin

Kang, Jian; Huo, Chang Hong; Li, Zhe; Li, Zuo Ping

doi:10.1016/j.cclet.2006.12.042

Cited by 20 publications

(10 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…57 (dd, J = 10.4, 5.3 Hz, H-1a, 1H), 4.40 (dd, J = 10.4, 3.1 Hz, H-1b, 1H), 5.08 (m, H-2, 1H), 4.32 (dd, J = 4.7, 3.2 Hz, H-3, 1H), 4.25(td, J = 5.5, 4.7, Hz, 1H) and 4.56 (t, J = 6.5 Hz, H-2′, 1H), whereas the carbons shifts of the respective centres were appeared at δ C 61.4, 52.0, 75.5, 72.4 and 72.7, respectively, which were in complete agreement with those of sphingolipids with a 2S,3S,4R,2R′ configuration(Muralidhar et al 2005;Kang et al 2007;Riaz et al 2007;Dongfack et al 2012). The optical rotations of 1 ([α] D = +41.0) and its methanolysis products ([α] D = 8.1 and +18.9) which were comparable with those of sphingolipids with a 2S,3S,4R,2′R configurations(Muralidhar et al 2005;Kang et al 2007;Dongfack et al 2012).…”

supporting

confidence: 79%

“…The optical rotations of 1 ([α] D = +41.0) and its methanolysis products ([α] D = 8.1 and +18.9) which were comparable with those of sphingolipids with a 2S,3S,4R,2′R configurations(Muralidhar et al 2005;Kang et al 2007;Dongfack et al 2012). Based on the above data and discussion, compound 1 was finally characterised as (2S,3S,4R)-2-{[(2R,5E)-2-hydroxyoctadec-5-enoyl] amino}hexaeicosane-1,3,4-triol.Compound 2 was isolated as colourless gummy solid.…”

mentioning

confidence: 62%

See 1 more Smart Citation

New lipoxygenase and cholinesterase inhibitory sphingolipids from Carthamus oxyacantha

Dilshad

Riaz

Saleem

et al. 2015

Natural Product Research

View full text Add to dashboard Cite

Two new sphingolipids: oxyacanthin A [(2S,3S,4R)-2-{[(2R,5E)-2-hydroxyoctadec-5-enoyl]amino}hexaeicosane-1,3,4-triol; 1] and B [(2S,3S,4R)-2-{[(2R,5E)-2-hydroxyoctadec-5-enoyl]amino}hexaeicosane-1,3,4-triol-1-O-β-D-glucopyranoside; 2], together with 1-octacosanol, β-sitosterol, β-sitosterol 3-O-β-D-glucopyranoside and luteolin 7-O-β-glucopyranoside were isolated from the methanolic extract of the whole plant of Carthamus oxyacantha. Their structures were elucidated using (1)H and (13)C NMR spectra and 2D NMR analyses (HMQC, HMBC and COSY) in combination with mass spectrometry (EI-MS, HR-EI-MS, FAB-MS and HR-FAB-MS) experiments and in comparison with the literature data of the related compounds. Both the compounds 1 and 2 showed inhibitory potential against lipoxygenase (LOX) in a concentration-dependent manner with IC50 values 83.3 ± 1.3 and 245.7 ± 1.1 µM, whereas compound 2 showed inhibition against enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values 65.3 ± 0.1 and 93.6 ± 0.1 µM, respectively.

show abstract

supporting

confidence: 79%

mentioning

confidence: 62%

New lipoxygenase and cholinesterase inhibitory sphingolipids from Carthamus oxyacantha

Dilshad

Riaz

Saleem

et al. 2015

Natural Product Research

View full text Add to dashboard Cite

show abstract

“…Flower heads of A. julibrissin are used in traditional medicine for the treatment of insomnia, anxiety, and depression (Kang et al 2007), while an infusion made from the stem bark is used in folk medicine to treat sprains, fractures, abscesses, hemorrhoids, boils, and ulcers (Orwa et al 2009;Kokila et al 2013). Active natural products of great pharmaceutical interest include triterpenoid saponins (Kinjo et al 1992;Liang et al 2005;Han et al 2011), phenolic glycosides (Jung et al 2004), and flavonoids (Lau et al 2007).…”

Section: Introductionmentioning

confidence: 99%

Genetic fidelity assessment of in vitro-regenerated plants of Albizia julibrissin using SCoT and IRAP fingerprinting

Rahmani

Pijut²,

Shabanian

et al. 2015

In Vitro Cell.Dev.Biol.-Plant

View full text Add to dashboard Cite

A protocol was established for callus induction and plant regeneration of Albizia julibrissin Durazz., a multipurpose tree. Calli were induced on hypocotyl explants excised from 10-to 14-d-old in vitro seedlings cultured on Murashige and Skoog (MS) medium supplemented with α -naphthaleneacetic acid (NAA) alone or in combination with 6-benzylaminopurine (BA) or 6-furfurylaminopurine (kinetin). The highest frequency of organogenic callus (82.2± 3.6%) was obtained on MS medium with 10.8 μM NAA and 4.4 μM BA. Calli were then cultured on MS medium with BA or zeatin, singly or in combination, for shoot regeneration. Calli cultured on MS medium with 13.2 μM BA and 4.6 μM zeatin produced the highest frequency of adventitious shoot regeneration (75.3±6.3%). Maximum rooting of shoots (73.3±5%) was achieved using half-strength MS medium with 4.9 μM indole-3-butyric acid. The genetic fidelity of 12 plants acclimatized to the greenhouse was assessed based on analyses of start codon targeted (SCoT) polymorphism and inter-retrotransposon amplified polymorphism (IRAP). The 14 SCoT and 7 IRAP adapted primers produced 71 and 34 scoreable fragments, of which 33 (46%) and 12 (35%) were polymorphic, respectively. The in vitro-raised plants exhibited 0.129-0.438 genetic distance from the mother plant and 0.000-0.788 distance from one another according to the SCoT and IRAP analyses. Although the culture method described here may not be suitable for clonal propagation of elite genotypes, it can be used for conservation of this plant.

show abstract

“…The seeds had anti-fertility effect on male rats [9] and antidiarhoeal activity studied on conventional rodents models of diarrhea [10]. In addition, the flowers are being commonly used to treat anxiety, depression and insomnia in traditional Chinese medicine [11]. In this study, we report evaluation of antipyretic, analgesic, estrogenic and antiinflammatory activities of different extracts of A. Lebbeck flowers.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Some Biological Activities of <i>Albizia lebbeck</i> Flowers

Farag¹,

Gamal²,

Kalil³

et al. 2013

View full text Add to dashboard Cite

Reviewing the current literature for the importance of the plant Albizia lebbeck L. growing worldwide revealed many biological interests. However, the species growing in Saudi Arabia has not received due attention. The present study was undertaken to study antipyretic, analgesic, estrogenic and anti-inflammatory activities of five different fractions from successive extraction of Albizia lebbeck flowers: n hexane, dichloromethane, ethyl acetate, n-butanol as well as the 70% total alcohol. The flowers showed reasonable antipyretic, analgesic, estrogenic and anti-inflammatory activities.

show abstract

New ceramides from the flower of Albizia julibrissin

Cited by 20 publications

References 3 publications

New lipoxygenase and cholinesterase inhibitory sphingolipids from Carthamus oxyacantha

New lipoxygenase and cholinesterase inhibitory sphingolipids from Carthamus oxyacantha

Genetic fidelity assessment of in vitro-regenerated plants of Albizia julibrissin using SCoT and IRAP fingerprinting

Evaluation of Some Biological Activities of <i>Albizia lebbeck</i> Flowers

Contact Info

Product

Resources

About

New ceramides from the flower of Albizia julibrissin

Cited by 20 publications

References 3 publications

New lipoxygenase and cholinesterase inhibitory sphingolipids from Carthamus oxyacantha

New lipoxygenase and cholinesterase inhibitory sphingolipids from Carthamus oxyacantha

Genetic fidelity assessment of in vitro-regenerated plants of Albizia julibrissin using SCoT and IRAP fingerprinting

Evaluation of Some Biological Activities of &lt;i&gt;Albizia lebbeck&lt;/i&gt; Flowers

Contact Info

Product

Resources

About

Evaluation of Some Biological Activities of <i>Albizia lebbeck</i> Flowers