New combined treatment of surgery, radiotherapy, and reconstruction in head and neck rhabdomyosarcoma in children: The amore protocol

Schouwenburg, Paul F.; Kupperman, D.S.; Bakker, F. P.; Blank, L.E.C.M.; Boer, H. B. De; Voûte, Tpa

doi:10.1002/(sici)1097-0347(199807)20:4<283::aid-hed1>3.0.co;2-v

Cited by 37 publications

(14 citation statements)

References 34 publications

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“…This strategy consists of consecutive Ablative surgery, MOuld technique afterloading brachytherapy and surgical REconstruction (AMORE). Earlier reports showed that the AMORE strategy is an effective local treatment modality in HNRMS patients, with survival figures comparable to other international study groups …”

supporting

confidence: 63%

“…Earlier reports showed that the AMORE strategy is an effective local treatment modality in HNRMS patients, with survival figures comparable to other international study groups. [9][10][11][12][13][14] The purpose of this study was to evaluate the longterm hearing loss in survivors of paediatric HNRMS. We performed audiological examinations in survivors treated at four large paediatric oncology centres: Great Ormond Street Hospital (GOSH), London, the Royal Marsden Hospital (RMH), Sutton, University College London Hospitals (UCLH), London, and the Emma Children's Hospital-Academic Medical Centre (EKZ-AMC), Amsterdam.…”

Section: Objectivesmentioning

confidence: 99%

See 1 more Smart Citation

Hearing loss in survivors of childhood head and neck rhabdomyosarcoma: a long‐term follow‐up study

Schoot

Theunissen

Slater

et al. 2016

Clinical Otolaryngology

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supporting

confidence: 63%

Section: Objectivesmentioning

confidence: 99%

Hearing loss in survivors of childhood head and neck rhabdomyosarcoma: a long‐term follow‐up study

Schoot

Theunissen

Slater

et al. 2016

Clinical Otolaryngology

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“…Therefore the ablative surgery, moulage brachytherapy and surgical reconstruction (AMORE) procedure was introduced in our institute in 1991 [54, 68]. After careful staging of children with histologically proven HNRMS, chemotherapy courses are given according to SIOP (or currently EpSSG) protocols.…”

Section: Treatment and Prognosismentioning

confidence: 99%

Imaging findings in craniofacial childhood rhabdomyosarcoma

et al. 2010

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Rhabdomyosarcoma (RMS) is the commonest paediatric soft-tissue sarcoma constituting 3–5% of all malignancies in childhood. RMS has a predilection for the head and neck area and tumours in this location account for 40% of all childhood RMS cases. In this review we address the clinical and imaging presentations of craniofacial RMS, discuss the most appropriate imaging techniques, present characteristic imaging features and offer an overview of differential diagnostic considerations. Post-treatment changes will be briefly addressed.

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“…2,3,8 Recent reports have advocated radical surgery for primary tumors and salvage treatment for the tumors at these sites, with promising results. 13,14 However, further studies are needed to compare the survival and long-term morbidity outcomes of these procedures with the standard chemotherapy and radiotherapy protocols for management of tumors at these sites. Although it may be argued that reducing the bulk of disease may improve survival, this must be balanced against the morbidity after such surgery.…”

Section: Commentmentioning

confidence: 99%