New developments in microextraction techniques in bioanalysis. A review

Ocaña-González, Juan Antonio; Fernández‐Torres, Rut; Bello‐López, Miguel Ángel; Ramos‐Payán, María

doi:10.1016/j.aca.2015.10.041

Cited by 186 publications

(59 citation statements)

References 174 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Ocana‐Gonzáles et al. summarized the use of all microextraction techniques in bioanalysis. The newest trend in SDME is utilization of ILs as the extraction phase, which is described in detail in a review article .…”

Section: Sdmementioning

confidence: 99%

Critical evaluation of microextraction pretreatment techniques – Part 1: Single drop and sorbent‐based techniques

Havlíková

Čabala

Pacáková

et al. 2018

J of Separation Science

View full text Add to dashboard Cite

Sample pretreatment techniques or preconcentration constitute a very important step before the analysis of environmental, clinical, pharmaceutical, and other complex samples. Thanks to extraction techniques it is possible to achieve higher method sensitivities and selectivities. Miniaturization microextraction methods make them more environmentally friendly and only small amounts of samples are required. In the past 30 years, a number of microextraction methods have been developed and used and are documented in thousands of articles. Many reviews have been written focusing on their use in specified professional fields or on the latest trends. Unfortunately, no uniform nomenclature has been introduced for these methods. Therefore, this review attempts to classify all the essential microextraction techniques and describes their advantages, disadvantages, and the latest innovations. The methods are divided into two main groups: single drop and sorbent‐based techniques according to the type of extraction phase.

show abstract

Section: Sdmementioning

confidence: 99%

Critical evaluation of microextraction pretreatment techniques – Part 1: Single drop and sorbent‐based techniques

Havlíková

Čabala

Pacáková

et al. 2018

J of Separation Science

View full text Add to dashboard Cite

show abstract

“…Miniaturization of instrumentation for sample treatment had experienced extensive development in the last three decades and liquid phase microextraction (LPME) had become one of the most convenient pretreatment techniques for samples with complex matrices . In 1986, Audunsson described extraction across a small segment of a thin sheet porous polymeric membrane impregnated with water immiscible organic solvent and termed the technique supported liquid membrane (SLM) extraction .…”

Section: Introductionmentioning

confidence: 99%

In‐line coupling of supported liquid membrane extraction across nanofibrous membrane to capillary electrophoresis for analysis of basic drugs from undiluted body fluids

Dvorak

Kubáň

2019

Electrophoresis

View full text Add to dashboard Cite

Planar polyamide 6 nanofibrous membrane was for the first time used in direct coupling of supported liquid membrane (SLM) extraction to CE analysis. Disposable microextraction device with the nanofibrous membrane was preassembled and stored for immediate use. The membrane in the device was impregnated with 1 µL of 1‐ethyl‐2‐nitrobenzene and the device was subsequently filled with 10 µL of acceptor solution (10 mM HCl) and 15 µL of donor solution (sample). The device was in‐line coupled to CE system for selective extraction and direct injection, separation and quantification of model basic drugs (nortriptyline, haloperidol, loperamide and papaverine) from standard saline solutions (150 mM NaCl) and from undiluted human body fluids (urine and blood plasma). Compared to standard polypropylene supporting material, the nanofibrous membrane demonstrated superior characteristics in terms of lower consumption of organic solvents, constant volumes of operational solutions, full transparency and possibility to preassemble the devices. Extraction parameters were better or comparable for the nanofibrous vs. the polypropylene membrane and the hyphenated SLM‐CE method with the nanofibrous membrane was characterized by good repeatability (RSD ≤ 11.3%), linearity (r2 ≥ 0.9953; 0.5–20 mg/L), sensitivity (LOD ≤ 0.4 mg/L) and transfer (27–126%) of the basic drugs.

show abstract

“…For acidic analytes (anionic species), the direction of the electrical field is In EME, the extraction efficiency and selectivity is determined by the direction and magnitude of the electrical field, and by the chemical composition of the SLM. An electrical field is used as driving force, so EME is a relatively rapid process and extractions are often finished in 5-10 minutes [7][8][9][10]. Target analytes are normally transferred into a few microliters of acceptor solution, so high analyte enrichment can be obtained [11,12].…”

Section: Introductionmentioning

confidence: 99%

Electromembrane extraction of polar basic drugs from plasma with pure bis(2-ethylhexyl) phosphite as supported liquid membrane

Huang

Seip

Gjelstad

et al. 2016

Analytica Chimica Acta

View full text Add to dashboard Cite

New developments in microextraction techniques in bioanalysis. A review

Cited by 186 publications

References 174 publications

Critical evaluation of microextraction pretreatment techniques – Part 1: Single drop and sorbent‐based techniques

Critical evaluation of microextraction pretreatment techniques – Part 1: Single drop and sorbent‐based techniques

In‐line coupling of supported liquid membrane extraction across nanofibrous membrane to capillary electrophoresis for analysis of basic drugs from undiluted body fluids

Electromembrane extraction of polar basic drugs from plasma with pure bis(2-ethylhexyl) phosphite as supported liquid membrane

Contact Info

Product

Resources

About