Nickel∗

Klein, Catherine B.; Costa, Max

doi:10.1016/b978-0-444-59453-2.00048-2

Cited by 16 publications

(12 citation statements)

References 206 publications

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“…The concentrations of iron chloride and nickel chloride were chosen on the basis of other reports and our earlier investigations (17, 12, 23). At 200 μM concentrations of the two trace elements, no changes in cell viability were observed.…”

Section: Discussionmentioning

confidence: 99%

Cell viability in normal fibroblasts and liver cancer cells after treatment with iron (III), nickel (II), and their mixture

Terpiłowska

Siwicka-Gieroba

Siwicki

2018

Journal of Veterinary Research

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IntroductionNickel and iron are very commonly occurring metals. Nickel is used in industry, but nowadays it is also used in medical biomaterials. Iron is an element necessary for cell metabolism and is used in diet supplements and biomaterials, whence it may be released along with nickel.Material and MethodsBALB/3T3 and HepG2 cells were incubated with iron chloride or nickel chloride at concentrations ranging from 100 to 1,400 μM. The following mixtures were used: iron chloride 200 μM plus nickel chloride 1,000 μM, or iron chloride 1,000 μM plus nickel chloride 200 μM. The cell viability was determined with MTT, LHD, and NRU tests.ResultsA decrease in cell viability was observed after incubating the BALB/3T3 and HepG2 cells with iron chloride or nickel chloride. A synergistic effect was observed after iron chloride 1,000 μM plus nickel chloride 200 μM treatment in all assays. Moreover, the same effect was observed in the pair iron chloride 200 μM plus nickel chloride 1,000 μM in the LDH and NRU assays.ConclusionsIron (III) and nickel (II) decrease cell viability. Iron chloride at a concentration of 200 μM protects mitochondria from nickel chloride toxicity.

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Section: Discussionmentioning

confidence: 99%

Cell viability in normal fibroblasts and liver cancer cells after treatment with iron (III), nickel (II), and their mixture

Terpiłowska

Siwicka-Gieroba

Siwicki

2018

Journal of Veterinary Research

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“…Nickel (Ni) compounds and metallic Ni have many industrial and commercial applications, including their use in stainless steel production, in a large series of metal alloys, as catalysts, in batteries, pigments, and ceramics [1]. An industrial sector in which Ni exposure can be particularly relevant is the production of special stainless steel in secondary steel foundries: the workers engaged in this industry are potentially exposed to various forms of airborne Ni, in particular during the operations of melting and casting and at all the stages of the process characterized by the need for high temperatures [2, 3].…”

Section: Introductionmentioning

confidence: 99%

Development of a New Sequential Extraction Procedure of Nickel Species on Workplace Airborne Particulate Matter: Assessing the Occupational Exposure to Carcinogenic Metal Species

Catalani

Fostinelli

Enrica

et al. 2018

International Journal of Analytical Chemistry

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Nickel (Ni) compounds and metallic Ni have many industrial and commercial applications, including their use in the manufacturing of stainless steel. Due to the specific toxicological properties of the different Ni species, there is a growing interest about the availability of analytical methods that allow specific risk assessment, particularly related to exposure to the Ni species classified as carcinogenic. In this paper, we described a speciation method of inorganic Ni compounds in airborne particulate matter, based on selective sequential extractions. The analytical method described in this paper allows the determination of soluble, sulfidic, metallic, and oxide Ni by a simple sequential extraction procedure and determination by Atomic Absorption Spectroscopy using small volumes of solutions and without long evaporation phases. The method has been initially set up on standard laboratory mixtures of known concentrations of different Ni salts. Then it has then been tested on airborne particulate matter (powder and filters) collected in different workstations of a large stainless steel production facility. The method has occurred effectively in the comparison of the obtained results with occupational exposure limit values set by the main international scientific and regulatory agencies for occupational safety and health, in order to prevent both toxic and carcinogenic effects in humans.

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“…Níquel: La mayor fuente de exposición de níquel con el ser humano son los alimentos, los efectos con el níquel residual se presentarán generalmente con alergias, dolores abdominales, aumento de glóbulos rojos, bronquitis, patologías relacionadas con el hígado y dentro de los casos más graves se puede presentar cáncer de pulmón. Por estos motivos el Departamento de Salud y Servicios Humanos de Estados Unidos ha clasificado al níquel como un compuesto carcinógeno [13], [14]. El níquel tiende a estar de manera natural en concentraciones bajas en el cacao, tomando en cuenta que el níquel es un metal que abunda en la superficie terrestre.…”

Section: Resultsunclassified

Análisis de cadmio, plomo, níquel y arsénico en plantas de cacao y derivados: Industria Alimentaria

Ordoñez-Araque

Lopez-Cortez

Casa-Lopez

et al. 2020

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INTRODUCCIÓN. El cacao es una materia prima producida principalmente en varios países de América, África y Asia. El cultivo de cacao es una de las principales actividades socio-económicas, en el Ecuador, siendo el primer exportador de cacao fino de aroma en grano de América. OBJETIVO. El presente artículo tiene como objetivo la revisión de investigaciones que analicen la problemática del contenido de cadmio, plomo, arsénico y níquel en los suelos de plantaciones y en productos derivados del cacao. MÉTODO. Se realizó una revisión sistemática consultando 18 artículos de las principales bases de datos. RESULTADOS. Se encontraron análisis de metales pesados relacionados con el cacao en distintos países del mundo. DISCUSIÓN Y CONCLUSIONES. Se ha encontrado que el cultivo de cacao y sus derivados postcosecha pueden tener concentraciones elevadas de cadmio, plomo, níquel y arsénico, la legislación no es lo suficientemente clara y en ciertos casos no se han desarrollado límites para ciertos metales pesados Trabajar en modelos predictivos para determinar una posible contaminación de metales pesados resulta indispensable para el sector industrial, así como las herramientas de mitigación en campo y producción.

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Nickel∗

Cited by 16 publications

References 206 publications

Cell viability in normal fibroblasts and liver cancer cells after treatment with iron (III), nickel (II), and their mixture

Cell viability in normal fibroblasts and liver cancer cells after treatment with iron (III), nickel (II), and their mixture

Development of a New Sequential Extraction Procedure of Nickel Species on Workplace Airborne Particulate Matter: Assessing the Occupational Exposure to Carcinogenic Metal Species

Análisis de cadmio, plomo, níquel y arsénico en plantas de cacao y derivados: Industria Alimentaria

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