Nigericin forms highly stable complexes with lithium and cesium

Alva, Raul; Lugo-R, J. Antonio; Arzt, Eduardo; Cerbón, Jorge; Rivera, Blanca E.; Toro, Mireya; Estrada-O, Sergio

doi:10.1007/bf00769539

Cited by 3 publications

(2 citation statements)

References 12 publications

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“…namycin, 4) [14] 、尼日利亚菌素(nigericin, 5) [15] 、尼日利亚菌素钠(nigericin sodium salt, 6) [16,17] 、30-O-乙酰基尼日利亚菌素(30-O-acetylnigericin, 7) [18] 、奥布菌素(abierixin, 8) [18,19] 、洋橄榄叶素(elaiophylin, 9) [20,21] 、surugapyrone A (10) [22] 和杀菌素 A (germicidin A , 11) [23,24] . [18,25] .…”

Section: 菌株鉴定结果unclassified

Cytotoxic Compounds from the DeepSea Sediment-Derived Streptomyces malaysiensis OUCMDZ-2167

王聪¹,

王立平²,

范杰³

et al. 2017

Chin. J. Org. Chem.

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Section: 菌株鉴定结果unclassified

Cytotoxic Compounds from the DeepSea Sediment-Derived Streptomyces malaysiensis OUCMDZ-2167

王聪¹,

王立平²,

范杰³

et al. 2017

Chin. J. Org. Chem.

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“…4 The main function of the ionophores is to minimize the energy needed to transfer metal ion across the ITIES. 5 Natural ionophores, such as gramacidin, valinomicin, nigercin and monensin have been used at the ITIES and for different purposes [6][7][8][9] related to metal ion transfer. Several synthetic ionophores have also been prepared that are able to transport metal ion across hydrophobic barriers and the ITIES; examples of these molecules are crown ethers and calixarenes, tetraethyl-p-tert-butyl calixarene tetraacetate.…”

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Electrochemical Investigation of the Ionophore Carboxylic “Lasalocid A” at the Water/1,2-dichloroethane Interface

Barrera-Cruz

Amador-Hernández

Velázquez-Manzanares

2012

J. Electrochem. Soc.

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This study describes the electrochemical behavior of the ionophore carboxylic "lasalocid A" at the water|1,2-dichlorotehane interface. It was carried out by means of cyclic voltammetry and ac impedance spectroscopy. The cyclic voltammetry studies showed that this ionophore is able to facilitate transfer of divalent metal ions across a liquid|liquid interface, and the differential capacitance measured as a function of ionophore concentration shows that lasalocid is absorbed at the interface and that it breaks the charge stratification when it transfers the metal ion across the interface. The interfacial complexation of the heavy metal and the transport across biological membranes is probably a key question in the heavy metal accumulation in a biological cell. Therefore the liquid|liquid interface could be a good model to mimic the metal transfer across a hydrophobic environment.Ion transfer across the biological cell is an important process for the economy of living systems. For this reason the scientific community has focused on this process in order to understand the behavior of membrane transporters at the biological membrane cell. 1 However, the complexity of the biological membrane makes it difficult to study the interaction lipid-protein (channel) in vivo. The water|membrane interface with regard to the structure and the characterization of membrane proteins is not easy to study because they are in a hydrophobic environment that makes it complicated to crystallize them for X-ray studies. 2 The interface of two immiscible electrolyte solutions (ITIES) has been a useful tool in representing the membrane|water interface in a simpler way since it can be manipulated electrochemically; thus the ITIES has been a model in the study of the charge and ion transfer across a hydrophobic environment, such as the transfer of metal ion across a biological membrane. 3 Another application is the selective metal extraction through the use of hydrophobic ionophores, which could have a great impact in the metallurgical industry. 4 The main function of the ionophores is to minimize the energy needed to transfer metal ion across the ITIES. 5 Natural ionophores, such as gramacidin, valinomicin, nigercin and monensin have been used at the ITIES and for different purposes 6-9 related to metal ion transfer. Several synthetic ionophores have also been prepared that are able to transport metal ion across hydrophobic barriers and the ITIES; examples of these molecules are crown ethers and calixarenes, tetraethyl-p-tert-butyl calixarene tetraacetate. 3,8,[10][11][12] In general, ionophores show similar behavior to the natural transporters, because they show a selectivity profile toward metal ions of biological importance, such as K + , Na + and Ca 2+ . [13][14][15] In previous studies on facilitated ion transfer, it was possible to determine of the complexating ligand and stability constants of the complexes formed between cation and ligand at the ITIES. 16 Proton transfer by novel 2-aminothiazole derivative at the water|1,2-dichloroetha...

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